Could an enzyme help people digest fructans?

NCT ID NCT05703009

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This Phase 2 study tested whether an oral enzyme called sacrosidase can reduce digestive symptoms in people with fructan intolerance. Twenty-five adults with confirmed fructan intolerance took either the enzyme or a placebo for one week, then switched after a washout period. The study measured changes in symptoms like bloating, pain, and gas.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sacrosidase (oral solution)

What this could lead to

If it works, this could point toward a treatment to ease digestive symptoms for people with fructan intolerance.

What could go wrong

This is a small, early Phase 2 pilot study with only 25 participants. Results may not be conclusive or apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston Specialists

    Boston, Massachusetts, 02111, United States