New combo therapy for MDS shows promise in early trial

NCT ID NCT04878432

First seen Oct 31, 2025 · Last updated May 15, 2026 · Updated 27 times

Summary

This study tested a new drug called sabatolimab added to standard chemotherapy for people with a bone marrow disorder called myelodysplastic syndrome (MDS) at intermediate to very high risk. The main goal was to check safety, and the study also looked at how many patients achieved complete remission within 12 months. The trial was stopped early, but results help guide future research.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Advent Health Orlando

    Orlando, Florida, 32803, United States

  • Arizona Oncology Associates

    Tucson, Arizona, 85745, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Duke Cancer Institute

    Durham, North Carolina, 27710, United States

  • Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • Mayo Clinic Arizona

    Phoenix, Arizona, 85054, United States

  • Mount Sinai Medical Center

    New York, New York, 10029-6574, United States

  • SCRI-Colorado Blood Cancer Institute

    Denver, Colorado, 80218, United States

  • Texas Oncology San Antonio USO

    San Antonio, Texas, 78240, United States

  • Tisch Hospital NYU Langone

    New York, New York, 10016, United States

  • Uni Of TX MD Anderson Cancer Cntr

    Houston, Texas, 77030, United States

  • Uni of Massachusetts Medical Center

    Worcester, Massachusetts, 01655, United States

  • University Hospitals Of Cleveland

    Cleveland, Ohio, 44106, United States

  • University Of Michigan

    Ann Arbor, Michigan, 48109, United States

  • Yale University School Of Medicine

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.