New drug combo explored for High-Risk blood cancer

NCT ID NCT04812548

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 27 times

Summary

This study tested a new drug called sabatolimab combined with two standard treatments (azacitidine and venetoclax) in 20 adults with high or very high risk myelodysplastic syndrome (MDS) who could not have intensive chemotherapy or a stem cell transplant. The goal was to see if the combination was safe and could help achieve complete remission, where signs of cancer disappear. The study was terminated early, so results are limited.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Brasschaat, 2930, Belgium

  • Novartis Investigative Site

    Marseille, 13273, France

  • Novartis Investigative Site

    Nice, 06202, France

  • Novartis Investigative Site

    Düsseldorf, 40479, Germany

  • Novartis Investigative Site

    Stuttgart, 70376, Germany

  • Novartis Investigative Site

    Alexandroupoli, Evros, 681 00, Greece

  • Novartis Investigative Site

    Pátrai, 265 00, Greece

  • Novartis Investigative Site

    Nyíregyháza, 4400, Hungary

  • Novartis Investigative Site

    Genova, GE, 16132, Italy

  • Novartis Investigative Site

    Barcelona, Catalonia, 08036, Spain

Conditions

Explore the condition pages connected to this study.