New combo therapy aims to tame deadly immune storm with fewer side effects
NCT ID NCT06160791
First seen Jan 04, 2026 · Last updated May 07, 2026 · Updated 20 times
Summary
This study tests a new treatment for adults with hemophagocytic lymphohistiocytosis (HLH), a rare condition where the immune system attacks the body. The treatment combines a targeted drug (ruxolitinib) with a shorter, milder version of standard therapy to reduce side effects while still controlling the disease. About 36 newly diagnosed adults will take part to see if this approach is safe and effective.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of California Davis Comprehensive Cancer Center
RECRUITINGSacramento, California, 95817, United States
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University of California, Irvine
RECRUITINGIrvine, California, 92697, United States
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Contact Email: •••••@•••••
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University of California, San Francisco
RECRUITINGSan Francisco, California, 94143, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Contact
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Conditions
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