New hope for rare blood cancer patients who Don't respond to standard therapy

NCT ID NCT00726232

First seen Oct 31, 2025 · Last updated May 10, 2026 · Updated 21 times

Summary

This study tested a drug called ruxolitinib in 73 people with advanced polycythemia vera or essential thrombocythemia, two rare blood cancers. Participants had not responded well to the standard treatment hydroxyurea. The goal was to see if ruxolitinib could safely control blood cell counts and reduce symptoms like an enlarged spleen. The study was stopped early, but results helped understand how the drug works in these patients.

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Contacts and locations

Locations

  • Study site

    Houston, Texas, 77030, United States

  • Study site

    Bergamo, Italy

  • Study site

    Florence, Italy

  • Study site

    Pavia, Italy

Conditions

Explore the condition pages connected to this study.