New hope for rare muscle disease: drug targets inflammation to preserve walking ability

NCT ID NCT06536166

Recruiting now Disease control Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether ruxolitinib, a drug that blocks a specific immune signal (interferon-γ), can help people with inclusion body myositis, a rare muscle disease that causes progressive weakness. About 80 adults aged 45 and older will receive either the drug or a placebo. The main goal is to see if treated patients can walk farther in 6 minutes than those on placebo, while also checking for side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

inclusion body myositis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INCLUSION BODY MYOSITIS, SPORADIC

Contacts and locations

Locations

CHU Caen Normandie
RECRUITING

Caen, France, 14000, France
CHU Nancy
RECRUITING

Nancy, France, 54035, France
CHU d'Angers
ENROLLING_BY_INVITATION

Angers, France, 49100, France
Centre hospitalier de la Côte Basque
ENROLLING_BY_INVITATION

Bayonne, France, 64109, France
Hôpital Bellevue, CHU Saint-Etienne
RECRUITING

Saint-Etienne, France, 42270, France
Hôpital CHU Jean Minjoz, CHU Besançon
ENROLLING_BY_INVITATION

Besançon, France, 25030, France
Hôpital Christian Cabrol, CHU Reims
RECRUITING

Reims, France, 51100, France
Hôpital Dupuytren, CHU de Limoges
RECRUITING

Limoges, France, 87000, France
Hôpital Gui de Chauliac, CHU de Montpellier
ENROLLING_BY_INVITATION

Montpellier, France, 34000, France
Hôpital Henri-Mondor, APHP
RECRUITING

Créteil, France, 94010, France
Hôpital Pasteur, CHU de Nice
RECRUITING

Nice, France, 06001, France
Hôpital Pellegrin - Tripode, CHU de Bordeaux
ACTIVE_NOT_RECRUITING

Bordeaux, France, 33076, France
Hôpital Pierre Wertheimer, CHU de Lyon
ACTIVE_NOT_RECRUITING

Bron, France, 69500, France
Hôpital Pierre-Paul Riquet, CHU de Toulouse
RECRUITING

Toulouse, France, 31059, France
Hôpital Pitié-Salpêtrière, APHP
RECRUITING

Paris, France, 75013, France
Hôpital Raymond Poincaré, APHP
ACTIVE_NOT_RECRUITING

Garches, France, 92380, France
Hôpital Roger Salengro, CHU de Lille
RECRUITING

Lille, France, 59037, France
Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg
ACTIVE_NOT_RECRUITING

Strasbourg, France, 67089, France
Hôpital de la Cavale Blanche, CHU de Brest
ENROLLING_BY_INVITATION

Brest, France, 29200, France
Hôpital de la Timone, APHM
NOT_YET_RECRUITING

Marseille, France, 13005, France
Hôtel-Dieu, CHU Nantes
ACTIVE_NOT_RECRUITING

Nantes, France, 44093, France