New hope for rare muscle disease: drug targets inflammation to preserve walking ability

NCT ID NCT06536166

Recruiting now Disease control Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 35 times

Summary

This study tests whether ruxolitinib, a drug that blocks a specific immune signal (interferon-γ), can help people with inclusion body myositis, a rare muscle disease that causes progressive weakness. About 80 adults aged 45 and older will receive either the drug or a placebo. The main goal is to see if treated patients can walk farther in 6 minutes than those on placebo, while also checking for side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

CHU Caen Normandie
RECRUITING

Caen, France, 14000, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
CHU Nancy
RECRUITING

Nancy, France, 54035, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
CHU d'Angers
ENROLLING_BY_INVITATION

Angers, France, 49100, France
Centre hospitalier de la Côte Basque
ENROLLING_BY_INVITATION

Bayonne, France, 64109, France
Hôpital Bellevue, CHU Saint-Etienne
RECRUITING

Saint-Etienne, France, 42270, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hôpital CHU Jean Minjoz, CHU Besançon
ENROLLING_BY_INVITATION

Besançon, France, 25030, France
Hôpital Christian Cabrol, CHU Reims
RECRUITING

Reims, France, 51100, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hôpital Dupuytren, CHU de Limoges
RECRUITING

Limoges, France, 87000, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hôpital Gui de Chauliac, CHU de Montpellier
ENROLLING_BY_INVITATION

Montpellier, France, 34000, France
Hôpital Henri-Mondor, APHP
RECRUITING

Créteil, France, 94010, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hôpital Pasteur, CHU de Nice
RECRUITING

Nice, France, 06001, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hôpital Pellegrin - Tripode, CHU de Bordeaux
ACTIVE_NOT_RECRUITING

Bordeaux, France, 33076, France
Hôpital Pierre Wertheimer, CHU de Lyon
ACTIVE_NOT_RECRUITING

Bron, France, 69500, France
Hôpital Pierre-Paul Riquet, CHU de Toulouse
RECRUITING

Toulouse, France, 31059, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hôpital Pitié-Salpêtrière, APHP
RECRUITING

Paris, France, 75013, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hôpital Raymond Poincaré, APHP
ACTIVE_NOT_RECRUITING

Garches, France, 92380, France
Hôpital Roger Salengro, CHU de Lille
RECRUITING

Lille, France, 59037, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg
ACTIVE_NOT_RECRUITING

Strasbourg, France, 67089, France
Hôpital de la Cavale Blanche, CHU de Brest
ENROLLING_BY_INVITATION

Brest, France, 29200, France
Hôpital de la Timone, APHM
NOT_YET_RECRUITING

Marseille, France, 13005, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hôtel-Dieu, CHU Nantes
ACTIVE_NOT_RECRUITING

Nantes, France, 44093, France

Conditions

Explore the condition pages connected to this study.

INCLUSION BODY MYOSITIS, SPORADIC