New cream shows promise for debilitating skin itch condition

NCT ID NCT05755438

Completed Symptom relief Sponsor: Incyte Corporation Source: ClinicalTrials.gov ↗

Summary

This study tested whether a cream containing ruxolitinib could safely reduce severe itch and improve skin lesions in people with prurigo nodularis, a chronic skin condition. Over 200 participants applied either the active cream or a placebo cream for 12 weeks, followed by an extended treatment period. The main goal was to see if the cream could significantly reduce the worst itch scores reported by patients.

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Contacts and locations

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Locations

Amsterdam University Medical Centre

Amsterdam, 1105 AZ, Netherlands
Asl 1 Avezzano L'Aquila Sulmona- Ospedale Regionale San Salvatore

Coppito, 67100, Italy
Austin Institute For Clinical Research Aicr Pflugerville

Pflugerville, Texas, 78660, United States
Az Sint-Lucas

Ghent, 09000, Belgium
Azienda Ospedaliera Universitaria Policlinico 'Federico Ii'

Naples, 80131, Italy
Azienda Ospedaliero Universitaria Policlinico G.Rodolico San Marco

Catania, 95123, Italy
Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia (Presidio Spedali Civili)

Brescia, 25123, Italy
Beacon Dermatology

Calgary, Alberta, T3E 0B2, Canada
Bravis Ziekenhuis

Bergen op Zoom, 4624 VT, Netherlands
Buenos Aires Skin

Ciudad Autonoma Buenos Aires, C1055AAO, Argentina
Cedic Centro de Investigaciones Clinicas

Ciudad Autonoma Buenos Aires, 01125, Argentina
Center For Clinical Studies

Webster, Texas, 77598, United States
Central Sooner Research

Norman, Oklahoma, 73071, United States
Centralny Szpital Kliniczny Mswia

Warsaw, 02-507, Poland
Centre Hospitalier Universitaire de Liege - Sart Tilman

Liège, 04000, Belgium
Centre Hospitalier Universitaire de Nantes (Chu de Nantes) - Hotel-Dieu

Nantes, 44093, France
Centre de Recherche Saint-Louis

Québec, Quebec, G1W 4R4, Canada
Centro Medico Skinmed

Las Condes, 7580206, Chile
Centro de Investigaciones Medicas Mar Del Plata

Mar del Plata, B7600FYK, Argentina
Centro de Investigaciones Medicas Tucuman

San Miguel de Tucumán, T4000AXL, Argentina
Chu Ucl Namur de Saint Elisabeth

Namur, 05000, Belgium
Ciec - Centro Internacional de Estudios Cli-Nicos

Santiago, 8420383, Chile
Clarkston Medical Group

Clarkston, Michigan, 48346, United States
Clinical Research Chile Spa.

Valdivia, 5090000, Chile
Clinical Research Group Sp. Z.O.O

Warsaw, 01-142, Poland
Cliniques Universitaires Ucl Saint-Luc

Brussels, 01200, Belgium
Complejo Hospitalario Universitario de Santiago

Santiago de Compostela, 15706, Spain
Conexa Investigacion Clinica S.A.

Buenos Aires, 01012, Argentina
Dermatology Associates Pc

Rockville, Maryland, 20850, United States
Dermatology Associates of Plymouth Meeting

Plymouth Meeting, Pennsylvania, 19462, United States
Dermeffects

London, Ontario, N6H 5L4, Canada
ETG LODZ

Lodz, 90-302, Poland
Fachklinik Bad Bentheim Dermatologie

Bad Bentheim, 48455, Germany
First Oc Dermatology

Fountain Valley, California, 92708, United States
Fondazione Policlinico Universitario Agostino Gemelli Irccs

Roma, 00137, Italy
Fundacion Scherbovsky

Mendoza, 05500, Argentina
Hautarztpraxis Dr. Med. Matthias Hoffmann

Witten, 58453, Germany
High-Med Przychodnia Specjalistycza

Warsaw, 01-817, Poland
Hospital General Unviersitario de Alicante

Alicante, 03010, Spain
Hospital Morvan

Brest, 29609, France
Hospital Prive D'Antony

Antony, 92160, France
Hospital Universitario Quironsalud Madrid

Pozuelo de Alarcón, 28223, Spain
Hospital Universitario Reina Sofia

Córdoba, 14004, Spain
Hospital de Manises

Manises, 46940, Spain
Instituto de Especialidades de La Salud Rosario

Rosario, S2000KPG, Argentina
International Clinical Research Tennessee Llc

Murfreesboro, Tennessee, 37130, United States
Johnson Dermatology

Fort Smith, Arkansas, 72916, United States
Kliniczny Szpital Wojewodzki Nr 1

Rzeszów, 35-055, Poland
Medical Dermatology Specialists Phoenix

Phoenix, Arizona, 85006, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Medisearch Clinical Trials

Saint Joseph, Missouri, 64506, United States
North Texas Center For Clinical Research Ntccr

Frisco, Texas, 75034, United States
Ospedali Riuniti Di Ancona

Torrette, 60123, Italy
Pratia McM Krakow

Krakow, 30-510, Poland
Premier Clinical Research

Spokane, Washington, 99204, United States
Psoriahue-Medicina Interdisciplinar

Ciudad Autonoma Buenos Aires, C1425DKG, Argentina
Research Toronto

Toronto, Ontario, M3H 5Y8, Canada
Revival Research Institute, Llc Troy

Troy, Michigan, 48084, United States
Simcomed Health Ltd

Barrie, Ontario, L4M 1G7, Canada
UC Health, Llc

Cincinnati, Ohio, 45219, United States
Ulb Hospital Erasme

Brussels, 01070, Belgium
Universitaetsklinikum Carl Gustav Carus Tu Dresden

Dresden, 01307, Germany
Universitair Ziekenhuis (Uz) Leuven

Leuven, 03000, Belgium
Universitair Ziekenhuis Gent

Ghent, 09000, Belgium
Universitats-Hautklink Tubingen

Tübingen, 72076, Germany
Universitatsklinikum Schleswig Holstein

Kiel, 24105, Germany
Universitatsmedizin Der Johannes Gutenberg-Universitat Mainz Iii

Mainz, 55131, Germany
University Hospital of Saint Etienne

Saint-Etienne, 42270, France
University Hospitals Cleveland Medical Center

Cleveland, Ohio, 44106, United States
University Medical Center Rwth Aachen

Aachen, 52074, Germany
Wake Forest University

Winston-Salem, North Carolina, 27157, United States

Conditions

Explore the condition pages connected to this study.

PRURIGO