Magnetic pulses to the brain may quiet multiple neurologic symptoms
NCT ID NCT06429748
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study investigates whether repetitive transcranial magnetic stimulation (rTMS) can reduce a range of neurologic symptoms, such as sleep difficulties, in adults aged 22 to 70. Participants receive rTMS sessions, and researchers track changes in symptom scores using patient questionnaires. The goal is to see if this non-invasive brain stimulation offers symptom relief and how long any benefits last.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- repetitive transcranial magnetic stimulation (rTMS)
- What this could lead to
- If it works, this could point toward a non-drug option for managing multiple neurologic symptoms, such as sleep problems.
- What could go wrong
- This is a small, early-stage study with only 20 participants, so results may not apply widely. The treatment may not provide lasting symptom relief.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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20 people
The number who actually took part.
- Started
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May 2024
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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22 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Adults, 22 to 70 years of age 2. Voluntarily provides written informed consent and agree to comply with study procedures, including attending all study visits and completing all study assessments. 3. Score \> or = 8 on ISI scale 4. If subject is on any psychiatric or sleep medication, dose must be stable for two weeks prior to enrollment and remain stable throughout the trial. 5. If female, not breastfeeding, no known or suspected pregnancy, a status of nonchildbearing potential or use of an acceptable form of birth control. 6. Subject on stable dose regime for other concurrent medications like hormonal therapy for menopause transition etc. Exclusion Criteria: 1. Subject meets any one or more of the contraindications for TMS Therapy per current treatment guidelines as determined by the PI. 2. History of head trauma associated with loss of consciousness or diagnosed as concussion. 3. History of fainting, syncope, hearing problems or ringing in the ears (tinnitus) 4. Has any metallic implant(s) in or near the head (e.g., pacemaker, defibrillator, neurostimulator, etc.) including any splinters, fragments, clips, etc. 5. Has an implanted stimulator device (including device leads) in or near the head. (e.g. deep brain stimulator, cochlear implant, vagus nerve stimulator.) 6. Has medication infusion device. 7. Subjects with any prior TMS or MRI complications, or any other issues/circumstance which, in the opinion of the investigator, might interfere with safety, study participation, or which might confound data interpretation. 8. PHQ-9 total score \> or = 10 or QIDS total score \> or = 11. 9. Drug abuse or dependence of the illicit substance. (Abuse or Dependence, as defined by DSM-V-TR) 10. Current diagnosis or known history of neurologic disease (e.g., epilepsy, convulsion, seizure) 11. Other known disorder (e.g., narcolepsy, a breathing-related sleep disorder like Obstructive Sleep Apnea, a circadian rhythm sleep-wake disorder, a parasomnia) as defined by DSM-V-TR. 12. Has a clinically significant abnormality on the screening examination. 13. Participation in any clinical trial with an investigational drug or device within the past month or concurrent with study participation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Charlotte Skin and Laser
Charlotte, North Carolina, 28207, United States
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