Major trial tests new shot to shield seniors from dangerous RSV

NCT ID NCT04908683

Completed Prevention Sponsor: Janssen Vaccines & Prevention B.V. Source: ClinicalTrials.gov ↗

Summary

This large, completed Phase 3 study tested whether a new vaccine could prevent serious lower respiratory tract disease caused by RSV in adults aged 60 and older. Over 25,000 participants were randomly assigned to receive either the experimental vaccine or a placebo shot. The main goal was to see if the vaccine reduced the number of confirmed, symptomatic RSV lung infections compared to the dummy injection.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

AMR Fort Myers Clinical Physiology Associates, an AMR company

Fort Myers, Florida, 33912, United States
AMR New Orleans, Formerly New Orleans Center for Clinical Research - New Orleans, an AMR company

New Orleans, Louisiana, 70119, United States
Accel Research Sites

Lakeland, Florida, 33803, United States
Accel Research Sites

Eatonton, Georgia, 31024, United States
Accellacare Research of Cary

Cary, North Carolina, 27518, United States
Accellacare Research of Cary

Raleigh, North Carolina, 27609, United States
Accellacare Research of Cary

Winston-Salem, North Carolina, 27103, United States
Achieve Clinical Research, LLC

Birmingham, Alabama, 35216, United States
Advanced Clinical Research

Boise, Idaho, 83642, United States
Advanced Clinical Research

Cedar Park, Texas, 78613, United States
Advanced Clinical Research

West Jordan, Utah, 84088, United States
Allergy Immunology Unit

Cape Town, 7700, South Africa
Altus Research, Inc

Lake Worth, Florida, 33461, United States
American Health Network, LLC

Charlotte, North Carolina, 28277, United States
Amherst Family Practice, PC

Winchester, Virginia, 22601, United States
Atlanta Center for Medical Research

Atlanta, Georgia, 30331, United States
Avail Clinical Research, LLC

DeLand, Florida, 32720, United States
Baptist Health Center For Clinical Research

Little Rock, Arkansas, 72205, United States
Be Part Yoluntu Centre

Western Cape, 7626, South Africa
Binhai County Center for Disease Control and Prevention

Yancheng, 224554, China
Bradford Royal Infirmary

Bradford, BD9 6RJ, United Kingdom
Buynak Clinical Research

Valparaiso, Indiana, 46383, United States
CENRESIN

Quilota, 2260734, Chile
CHEAR Center, LLC

The Bronx, New York, 10455, United States
CMIP - Centro Mineiro de Pesquisa Ltda

Juiz de Fora, 36010 570, Brazil
CPQuali Pesquisa Clinica LTDA ME

São Paulo, 01228-900, Brazil
CRISMO Bertha Gxowa Research Centre

Johannesburg, 1401, South Africa
Centennial Medical Group

Elkridge, Maryland, 21075, United States
Center for Clinical and Basic Research

Tallinn, 10128, Estonia
Centex Studies, Inc.

Lake Charles, Louisiana, 70601, United States
Central Kentucky Research Associates, Inc.

Lexington, Kentucky, 40509, United States
Central Maine Medical Center

Lewiston, Maine, 04240, United States
Central Phoenix Medical Clinic

Phoenix, Arizona, 85020, United States
Central Research Associates, Inc.

Birmingham, Alabama, 35205, United States
Central Texas Clinical Research

Austin, Texas, 78705, United States
Centro de Estudios Clínicos e Investigación Médica (CeCim)

Santiago, 8331143, Chile
Centro de Investigacion del Maule

Talca, 3465586, Chile
Centrum Medyczne Pratia Poznan

Skorzewo, 60 185, Poland
Chang Gung Memorial Hospital- Linkou

Taoyuan, 33305, Taiwan
Charlottesville Medical Research Center, LLC

Charlottesville, Virginia, 22911, United States
China Medical University Hospital

Taichung, 40447, Taiwan
Christie Clinic

Champaign, Illinois, 61822, United States
Clinical NeuroScience Solutions Inc

Orlando, Florida, 32801, United States
Clinical Research Associates Inc

Nashville, Tennessee, 37203, United States
Clinical Research Associates of Tidewater

Norfolk, Virginia, 23507, United States
Clinical Research Atlanta

Stockbridge, Georgia, 30281, United States
Clinical Research Centre

Tartu, 50106, Estonia
Clinical Research Consortium Arizona

Tempe, Arizona, 85283, United States
Clinical Research Consortium, an AMR company

Las Vegas, Nevada, 89119, United States
Clinical Research Institute of Southern Oregon, P.C.

Grants Pass, Oregon, 97527, United States
Clinical Research Institute of Southern Oregon, P.C.

Medford, Oregon, 97504, United States
Clinical Research of South Florida, an AMR Company

Coral Gables, Florida, 33134, United States
Clinical Site Partners, LLC

Miami, Florida, 33186, United States
Clinical Trials of America

Monroe, Louisiana, 71201, United States
Clinical Trials of Texas Inc

San Antonio, Texas, 78229, United States
Clinresco Centres Pty Ltd

Johannesburg, 1619, South Africa
Coastal Carolina Research Center

Mt. Pleasant, South Carolina, 29464, United States
Coastal Clinical Research, Inc

Mobile, Alabama, 36608, United States
Compass Research LLC

Leesburg, Florida, 34748, United States
DBC Research

Tamarac, Florida, 33321, United States
DIEX Recherche Joliette Inc.

Saint-Charles-Borromée, Quebec, J6E 2B4, Canada
DIEX Recherche Quebec Inc.

Québec, Quebec, G1N 4V3, Canada
DIEX Recherche Sherbrooke Inc

Sherbrooke, Quebec, J1L 0H8, Canada
DIEX Recherche Victoriaville Inc.

Victoriaville, Quebec, G6P 6P6, Canada
DJW Research

Krugersdorp, 1739, South Africa
DM Clinical Research

Tomball, Texas, 77375, United States
Donghai County Center for Disease prevention and Control

Lianyungang, 222200, China
Encompass Clinical Research

Spring Valley, California, 91978, United States
Espoon rokotetutkimusklinikka

Espoo, 2230, Finland
Etelä-Helsingin rokotetutkimusklinikka

Helsinki, 00100, Finland
Finger Lakes Clinical Research

Rochester, New York, 14618, United States
Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto Hospital de Base

São José do Rio Preto, 15090 000, Brazil
Funing County Center for Disease Control and Prevention

Yancheng, 224435, China
FutureMeds Bridle Clinic

Bromborough, CH62 6EE, United Kingdom
FutureMeds Soho Health Centre

Birmingham, B21 9RY, United Kingdom
Global Clin Trials Pretoria

Pretoria, 0001, South Africa
Harlem Hospital Center

New York, New York, 10027, United States
Harmony Clinical Research Inc

North Miami Beach, Florida, 33162, United States
Headlands Research Orlando

Orlando, Florida, 32806, United States
Health Research of Hampton Roads, Inc

Newport News, Virginia, 23606, United States
Healthcare Clinical Data Inc.

North Miami, Florida, 33161, United States
Heartland Clinical Research

Wichita, Kansas, 67207, United States
Heartland Research Associates, LLC

Augusta, Kansas, 67010, United States
Heartland Research Associates, LLC

Newton, Kansas, 67114, United States
Hope Research Institute

Peoria, Arizona, 85381, United States
Hope clinical Research LLC

Canoga Park, California, 91303, United States
Hospital das Clinicas de Porto Alegre

Porto Alegre, 90035-903, Brazil
Iatros International

Bloemfontein, 9301, South Africa
Itä-Helsingin rokotetutkimusklinikka

Helsinki, 00930, Finland
JEM Research LLC

Atlantis, Florida, 33462, United States
Jacksonville Center For Clinical Research

Jacksonville, Florida, 32216, United States
Jefferson City Medical Group Family

Jefferson City, Missouri, 65109, United States
Johnson County Clin-Trials

Lenexa, Kansas, 66219, United States
Josha Research

Bloemfontein, 9301, South Africa
Järvenpään rokotetutkimusklinikka

Jarvenpaa, 04400, Finland
KO MED Centra Kliniczne LUBLIN

Lublin, 20 362, Poland
KO MED Centra Kliniczne Pulawy

Puławy, 24-100, Poland
KO MED Centra Kliniczne Zamosc

Zamość, 22 400, Poland
KO-MED Centra Kliniczne Staszow

Staszów, 28 200, Poland
Kaohsiung Medical University Chung Ho Memorial Hospital

Kaohsiung City, 80756, Taiwan
King Chulalongkorn Memorial Hospital

Pathumwan, 10330, Thailand
Kokkolan rokotetutkimusklinikka

Kokkola, 67100, Finland
LMC Clinical Research Inc. (Bayview)

Toronto, Ontario, M4G 3E8, Canada
LMC Clinical Research dba Manna Research Inc. Burlington

Burlington, Ontario, L7R 1E2, Canada
LMC Clinical Research dba Manna Research Inc. Montreal

Pointe-Claire, Quebec, H9R 4S3, Canada
LMC Clinical Research dba Manna Research Inc. Quebec City

Lévis, Quebec, G6W 0M5, Canada
LMC Clinical Research dba Manna Research Inc. Toronto

Toronto, Ontario, M9W 4L6, Canada
Lakeland Clinical Trials

Hamilton, 3200, New Zealand
Lakeland Clinical Trials

Rotorua, 3010, New Zealand
Lakeland Clinical Trials

Upper Hutt, 5018, New Zealand
Lynn Health Science Institute

Oklahoma City, Oklahoma, 73112, United States
Lynn Institute of Norman

Norman, Oklahoma, 73072, United States
M3-Emerging Medical Research

Durham, North Carolina, 27704, United States
Madibeng Centre for Research

Brits, 250, South Africa
Maharaj Nakorn Chiang Mai hospital Faculty of Medicine

Muang, 50200, Thailand
Martine Diagnostic Clinic

Tomball, Texas, 77375, United States
Mater Hospital Brisbane

South Brisbane, 4101, Australia
MedPharmics - Biloxi

Biloxi, Mississippi, 39531, United States
Medication Management LLC

Greensboro, North Carolina, 27401, United States
Medisphere Medical Research Center, Llc

Evansville, Indiana, 47714, United States
Medpharmics, LLC

Phoenix, Arizona, 85379, United States
Medpharmics, LLC

Kenner, Louisiana, 70065, United States
Medpharmics, LLC

Lafayette, Louisiana, 70508, United States
Medpharmics, LLC

Albuquerque, New Mexico, 87102, United States
Mercury Street Medical Group, PLLC

Butte, Montana, 59701, United States
Meridian Clinical Research - Dakota Dunes

Dakota Dunes, South Dakota, 57049, United States
Meridian Clinical Research - Omaha

Omaha, Nebraska, 68134, United States
Meridian Clinical Research, LLC

Savannah, Georgia, 31406, United States
Meridian Clinical Research, LLC

Norfolk, Nebraska, 68701, United States
Meridian Clinical Research, LLC

Endwell, New York, 13760, United States
Monroe Biomedical Research

Monroe, North Carolina, 28112, United States
National Taiwan University Hospital

Taipei, 10002, Taiwan
New Horizon Research Center

Miami, Florida, 33165, United States
Newtown Clinical Research

Newtown, 2113, South Africa
North Manchester General Hospital

Manchester, M8 5RB, United Kingdom
North Texas Infectious Diseases Consultants

Dallas, Texas, 75246, United States
Northside Health

Coffs Harbour, 2450, Australia
OU Innomedica

Tallinn, 10117, Estonia
Okanagan Clinical Trials

Kelowna, British Columbia, V1Y 1Z9, Canada
Omega Medical Research

Warwick, Rhode Island, 02886, United States
Optimal Clinical Trials

Auckland, 1010, New Zealand
Optimal Research

Huntsville, Alabama, 35802, United States
Optimal Research

San Diego, California, 92108, United States
Optimal Research

Melbourne, Florida, 32934, United States
Optimal Research

Peoria, Illinois, 61614, United States
Optimal Research

Rockville, Maryland, 20850, United States
Optimal Research

Austin, Texas, 78705, United States
Oulun rokotetutkimusklinikka

Oulu, 90220, Finland
P3 Reaearch Wellington

Wellington, 6021, New Zealand
P3 Research Limited Kapiti

Paraparaumu, 5032, New Zealand
P3 Research Ltd

Havelock North, 3410, New Zealand
P3 Research Ltd

Palmerston North, 4414, New Zealand
P3 Research Ltd

Tauranga, 3110, New Zealand
PMG Research of Bristol

Bristol, Tennessee, 37620, United States
PMG Research of Charleston, LLC

Mt. Pleasant, South Carolina, 29464, United States
PMG Research of Wilmington, LLC

Wilmington, North Carolina, 28401, United States
Paarl Research Centre

Paarl, 7646, South Africa
Palm Beach Research Center

West Palm Beach, Florida, 33409, United States
Panthera Biopartners

Glasgow, G51 4TF, United Kingdom
Panthera Biopartners

Preston, PR2 9RB, United Kingdom
Panthera Biopartners

Reading, RG2 9LH, United Kingdom
Paradigm Clinical Research Centers, Inc.

Redding, California, 96001, United States
Paradigm Clinical Research Centers, Inc.

Wheat Ridge, Colorado, 80033, United States
Paratus Clinical Canberra Clinic

Bruce, 2617, Australia
Paratus Clinical Kanwal Clinic

Kanwal, 2059, Australia
Porin rokotetutkimusklinikka

Pori, 28100, Finland
Preferred Primary Care Physicians Research

Pittsburgh, Pennsylvania, 15243, United States
Preferred Primary Care Physicians Research

Uniontown, Pennsylvania, 15401, United States
Prestige Clinical Research Center, Inc.

Coral Gables, Florida, 33134, United States
Progressive Medical Research

Port Orange, Florida, 32127, United States
REIMED Vosloorus

Vosloorus, 01475, South Africa
Rancho Paseo Medical Group

Banning, California, 92220, United States
Rapid Medical Research

Cleveland, Ohio, 44122, United States
Regional Clinical Research, Inc.

Endwell, New York, 13760, United States
Research Your Health

Plano, Texas, 75093, United States
Richmond Behavioral Associates

Staten Island, New York, 10312, United States
Royal Thai Army, Afrims

Bangkok, 10400, Thailand
Sandhill Research

St. Petersburg, Florida, 33709, United States
Seinäjoen rokotetutkimusklinikka

Seinäjoki, 60100, Finland
Siriraj Hospital

Bangkok, 10700, Thailand
Southern Clinical Trials Tasman

Main Road Stoke, 7011, New Zealand
Southern Clinical Trials Totara Clinical Research

Auckland, 0600, New Zealand
Southern Clinical Trials, Christchurch

Christchurch, 8013, New Zealand
Southern Clinical Trials, Waitemata

Auckland, 0626, New Zealand
Spartanburg Medical Research

Spartanburg, South Carolina, 29303, United States
Spectrum Medical, Inc

Danville, Virginia, 24541, United States
Srinagarind Hospital

Khon Kaen, 40002, Thailand
Stanza Clinical Research Centre : Mamelodi

Mamelodi East, 0122, South Africa
Suncoast Research Associates, LLC

Miami, Florida, 33173, United States
Suncoast Research Group

Miami, Florida, 33135, United States
Sundance Clinical Research

St Louis, Missouri, 63141, United States
Synergy Biomed Research Institute (SBRI)

East London, 5241, South Africa
Synexus Clinical Research US Inc

Birmingham, Alabama, 35211, United States
Synexus Clinical Research US Inc

Chandler, Arizona, 85224, United States
Synexus Clinical Research US Inc

Tucson, Arizona, 85741, United States
Synexus Clinical Research US Inc

Cerritos, California, 90703, United States
Synexus Clinical Research US Inc

Vista, California, 92083, United States
Synexus Clinical Research US Inc

Aurora, Colorado, 80014, United States
Synexus Clinical Research US Inc

Orlando, Florida, 32806, United States
Synexus Clinical Research US Inc

Pinellas Park, Florida, 33781, United States
Synexus Clinical Research US Inc

Atlanta, Georgia, 30328, United States
Synexus Clinical Research US Inc

Chicago, Illinois, 60602, United States
Synexus Clinical Research US Inc

Richfield, Minnesota, 55423, United States
Synexus Clinical Research US Inc

St Louis, Missouri, 63141, United States
Synexus Clinical Research US Inc

Omaha, Nebraska, 68144, United States
Synexus Clinical Research US Inc

Henderson, Nevada, 89052, United States
Synexus Clinical Research US Inc

Manhattan, New York, 10017, United States
Synexus Clinical Research US Inc

Akron, Ohio, 44311, United States
Synexus Clinical Research US Inc

Cincinnati, Ohio, 45236, United States
Synexus Clinical Research US Inc

Columbus, Ohio, 43212, United States
Synexus Clinical Research US Inc

Anderson, South Carolina, 29621-2062, United States
Synexus Clinical Research US Inc

Dallas, Texas, 75231, United States
Synexus Clinical Research US Inc

San Antonio, Texas, 78229, United States
Synexus Clinical Research US Inc

Layton, Utah, 84041, United States
Synexus Clinical Research US Inc

Murray, Utah, 84123, United States
Synexus Helderberg Clinical Research Centre

Cape Town, 7130, South Africa
Synexus Hexham General Hospital

Hexham, NE46 1QJ, United Kingdom
Synexus Lancashire Clinical Research Centre

Chorley, PR7 7NA, United Kingdom
Synexus Manchester Clinical Research Center

Manchester, M15 6SX, United Kingdom
Synexus Merseyside Clinical Research Centre

Liverpool, L22 0LG, United Kingdom
Synexus Midlands Clinical Research Centre

Birmingham, B15 2SQ, United Kingdom
Synexus Polska Sp z o o

Lodz, 90 127, Poland
Synexus Polska Sp z o o Oddzial w Katowicach

Katowice, 40 040, Poland
Synexus Polska Sp z o o Oddzial w Warszawie

Warsaw, 623832, Poland
Synexus Polska Sp z o o Oddzial we Wroclawiu

Wroclaw, 50 381, Poland
Synexus Polska Sp. z o.o. Oddzial w Czestochowie

Częstochowa, 42-202, Poland
Synexus Polska Sp. z o.o. Oddzial w Gdansku

Gdansk, 80-382, Poland
Synexus Polska Sp. z.o.o. Oddzial w Poznaniu

Poznan, 60-702, Poland
Synexus Scm Sp Z o o Oddzial Gdynia

Gdynia, 81 537, Poland
Synexus Scotland Clinical Research Centre

Glasgow, United Kingdom
Synexus Wales Clinical Research Center

Cardiff, CF15 9SS, United Kingdom
Synexus Watermeyer

Pretoria, South Africa
TASK Central

Cape Town, 7530, South Africa
TASK Central

George, 06530, South Africa
TREAD Research Tygerberg Hospital

Cape Town, 7500, South Africa
Taipei Medical University

Taipei, 110, Taiwan
Taipei Municipal Wanfang Hospital

Taipei, 116, Taiwan
Taipei Veterans General Hospital

Taipei, 11217, Taiwan
Tampereen rokotetutkimusklinikka

Tampere, 33100, Finland
Tekton Research Inc.

Fort Collins, Colorado, 80528, United States
Tekton Research Inc.

Longmont, Colorado, 80501, United States
Tekton Research Inc.

Yukon, Oklahoma, 73099, United States
Tekton Research Inc.

Austin, Texas, 78745, United States
Tekton Research Inc.

Beaumont, Texas, 78745, United States
Tekton Research Inc.

San Antonio, Texas, 78240, United States
Texas Center for Drug Development Inc

Houston, Texas, 77081, United States
The Aurum Institute Rustenburg Clinical Research Site

Rustenburg, 300, South Africa
The Center for Pharmaceutical Research (CPR)

Kansas City, Missouri, 64114, United States
The Iowa Clinic, P.C.

West Des Moines, Iowa, 50266, United States
The South Bend Clinic Center for Research

South Bend, Indiana, 46617-2808, United States
The Vaccine Trial Center(VTC), Faculty of Tropical Medicine

Bangkok, 10400, Thailand
Tiervlei Trial Centre

Cape Town, 7530, South Africa
Tri-Service General Hospital

Taipei, 11490, Taiwan
Trial Management Associates, LLC

Wilmington, North Carolina, 28401, United States
Tulane University School of Medicine

New Orleans, Louisiana, 70112, United States
Turun rokotetutkimusklinikka

Turku, 20520, Finland
UFRR - Universidade Federal de Roraima

Boa Vista, 69304-000, Brazil
University Hospital of North Tees

Stockton-on-Tees, TS19 8PE, United Kingdom
University of Louisville

Louisville, Kentucky, 40202, United States
VGR & NOCCR - Knoxville

Knoxville, Tennessee, 37920, United States
Velocity Clinical Research

Cincinnati, Ohio, 45242, United States
Velocity Clinical Research, Hallandale Beach

Hallandale, Florida, 33009, United States
Velocity Clinical Research, Inc.

Edgewater, Florida, 32132, United States
Velocity Clinical Research, Inc.

Gaffney, South Carolina, 29340, United States
Velocity Clinical Research, San Diego

La Mesa, California, 91942, United States
Vilo Research Group Inc

Houston, Texas, 77017, United States
VitaLink Research Spartanburg

Spartanburg, South Carolina, 29303, United States
Wake Research Associates

Raleigh, North Carolina, 27612, United States
Welkom Clinical Trial Centre

Welkom, 9460, South Africa
Westside Center for Clinical Research

Jacksonville, Florida, 32205, United States
Worthwhile Clinical trials

Johannesburg, 1501, South Africa
eStudySite

Chula Vista, California, 919111, United States

Conditions

Explore the condition pages connected to this study.

LOWER RESPIRATORY TRACT DISEASE RESPIRATORY SYNCYTIAL VIRUSES