New surgery aims to stop chronic pain after breast cancer surgery

NCT ID NCT06580951

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 29 times

Summary

This study tests a procedure called regenerative peripheral nerve interface (RPNI) done at the same time as mastectomy with breast reconstruction. The goal is to prevent long-term nerve pain (neuroma-related post-breast surgery pain syndrome) that can occur after surgery. About 200 adult women will be randomly assigned to receive either standard surgery alone or standard surgery plus RPNI. Participants will report their pain and quality of life through surveys before surgery and at several points over 12 months.

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