Modified virus fights advanced cancers in early safety trial
NCT ID NCT04735978
Summary
This early-stage study is testing a new treatment called RP3, which is a genetically modified virus designed to attack cancer cells and boost the immune system. It will be given to about 123 adults with advanced solid tumors that have not responded to standard treatments, both by itself and combined with an immunotherapy drug. The main goals are to check the safety of RP3 and find the best dose for future studies.
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Contacts and locations
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Locations
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Churchill Hospital
Oxford, OX3 9DU, United Kingdom
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Hospital Clinic Barcelona
Barcelona, 08036, Spain
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Hospital Clinico Universitario de Valencia
Valencia, 46010, Spain
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Laboratoire de Recherche Translationnelle en Immunotherapie (LRTI), Gustave Roussy
Villejuif, 94805, France
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
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START Madrid CIO Clara Campal, Hospital Universitario HM Sanchinarro Unidad de Ensayos Fase I Panta 3
Madrid, 28050, Spain
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The Clatterbridge Cancer Centre NHS Foundation Trust
Bebington, Merseyside, CH63 4JY, United Kingdom
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The Royal Marsden NHS Foundation Trust
London, SW3 6JJ, United Kingdom
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UPMC Hillman Cancer Center
Pittsburgh, Pennsylvania, 15232, United States
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University General Hospital Attikon
Athens, 12462, Greece
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University of Athens
Athens, 11527, Greece
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University of Iowa
Iowa City, Iowa, 52242, United States
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Vall d'Hebron Hospital Hospital Universitario Vall d´Hebron (Vall d'Hebron University Hospital)
Barcelona, 08035, Spain
Conditions
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