New drug hopes to boost Radiation's punch against tough gut cancers

NCT ID NCT02381561

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study tests an oral drug called ropidoxuridine (IPdR) in people with advanced gastrointestinal cancers that cannot be cured. The goal is to find the safest dose and see if it can make radiation therapy more effective at shrinking tumors. Nineteen participants with cancers of the esophagus, stomach, liver, pancreas, or bowel are enrolled.

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Conditions

The condition(s) this trial relates to.

bile duct carcinoma carcinoma of esophagus colon carcinoma colonic neoplasm esophageal cancer Esophageal Neoplasms gastric cancer gastric carcinoma gastric neoplasm liver cancer Liver Neoplasms malignant colon neoplasm malignant pancreatic neoplasm rectal cancer rectal neoplasm small intestine cancer small intestine carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States