New drug combo shows promise for rare blood cancer before transplant

NCT ID NCT02223208

First seen Jan 04, 2026 · Last updated May 14, 2026 · Updated 23 times

Summary

This study tests adding romidepsin to standard chemotherapy (CHOEP) in young adults (ages 18-65) with newly diagnosed peripheral T-cell lymphoma. The goal is to see if this combination is safe and effective before a stem cell transplant. About 89 participants will receive the treatment, with researchers monitoring side effects and how long the cancer stays away.

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Contacts and locations

Locations

  • A.O. di Perugia - Santa Maria della Misericordia

    Perugia, 06132, Italy

  • AO Città della Salute e della Scienza - Ematologia 1U

    Torino, TO, 10126, Italy

  • AO Città della Salute e della Scienza - SC Ematologia

    Torino, TO, 10126, Italy

  • AO Ospedali Riuniti Villa Sofia - Cervello (Presidio Cervello)

    Palermo, PA, 90146, Italy

  • AOU "Santa Maria della Misericordia"

    Udine, UD, 33100, Italy

  • AOU di Parma

    Parma, PR, 43100, Italy

  • Azienda Ospedaliera Ospedale Niguarda Ca' Granda

    Milan, MI, 20162, Italy

  • Azienda Ospedaliera S.Croce e Carle

    Cuneo, CN, 12100, Italy

  • Fondazione IRCCS "Istituto Nazionale dei Tumori"

    Milan, MI, 20133, Italy

  • Fondazione IRCCS - Policlinico San Matteo

    Pavia, PV, 27100, Italy

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

    Milan, MI, 20122, Italy

  • IRCCS AOU San Martino - Clinica Ematologica

    Genova, GE, 16321, Italy

  • IRCCS AOU San Martino - UO Ematologia 1

    Genova, GE, 16321, Italy

  • IRCCS Arcispedale "Santa Maria Nuova"

    Reggio Emilia, RE, 42123, Italy

  • IRCCS Centro di Riferimento Oncologico (CRO)

    Aviano, PN, 33081, Italy

  • Istituto Clinico Humanitas

    Rozzano, Milano, 20089, Italy

  • Istituto Nazionale Tumori IRCCS - Fondazione G. Pascale

    Naples, 80131, Italy

  • Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (I.R.S.T.) - Sede di Meldola

    Meldola, FC, 47014, Italy

  • Ospedale Borgo Roma

    Verona, VR, 37134, Italy

  • Ospedale Businco

    Cagliari, CA, 09121, Italy

  • Ospedale G. Da Saliceto - AUSL di Piacenza

    Piacenza, 29121, Italy

  • Ospedale Maggiore della Carità - SCDU Ematologia

    Novara, 28100, Italy

  • Ospedale SS. Antonio e Biagio e Cesare Arrigo

    Alessandria, AL, 15121, Italy

  • Ospedale degli Infermi

    Rimini, RN, 47900, Italy

  • Policlinico S. Orsola Malpighi

    Bologna, BO, 40138, Italy

  • Spedali Civili

    Brescia, BS, 26123, Italy

  • UO Ematologia Ospedale S.Maria delle Croci

    Ravenna, 48121, Italy

Conditions

Explore the condition pages connected to this study.