New hope for lung cancer patients Who've tried everything?
NCT ID NCT06879717
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tests a new drug called roginolisib combined with two other drugs (dostarlimab and docetaxel) in 45 adults with advanced non-squamous lung cancer that has worsened after standard treatments. The main goals are to see if the combo is safe and whether it reduces certain immune cells in the blood. It is an early-stage study, so the focus is on safety and immune response rather than cure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- roginolisib (tablet), dostarlimab (IV infusion), docetaxel (IV infusion)
- What this could lead to
- If successful, this could offer a new treatment option for people with advanced lung cancer who have run out of standard therapies.
- What could go wrong
- This is an early-phase trial with only 45 participants, so results may not apply to everyone. The combination may cause significant side effects or fail to shrink tumors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ADVANCED NON SQUAMOUS NSCLC are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
AZ Delta VZW
Roeselare, 8800, Belgium
-
Antwerp University Hospital
Antwerp, 2650, Belgium
-
Hospital Universitari Son Espases
Palma, 07120, Spain
-
Hospital Universitario y Politécnico La Fe
Valencia, 46026, Spain
-
Humanitas University, Department of Medical Oncology
Rozzano, Milan, 20072, Italy
-
Institut Català d'Oncologia Hospitalet
Barcelona, 08908, Spain
-
Istituto Romagnolo per lo studio dei Tumori "Dino Amadori"
Meldola, Forlì-Cesena, 47014, Italy