New Alzheimer's drug aims to clear brain plaques

NCT ID NCT04639050

Ongoing Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 25 times

Summary

This study tests an experimental drug called RO7126209 in 241 people with early to moderate Alzheimer's disease. The goal is to see if the drug is safe and how it affects amyloid plaques in the brain. Participants receive multiple doses of the drug or a placebo through an IV.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Abington Neurological Associates

Abington, Pennsylvania, 19001, United States
Advent Health Orlando

Orlando, Florida, 32804, United States
Alfred Hospital

Melbourne, Victoria, 3004, Australia
Alzheimer's Research and Treatment Center

Stuart, Florida, 34997, United States
Alzheimer's Research and Treatment Center - Columbus

Columbus, Georgia, 31904, United States
Alzheimer?s Research and Treatment Center

Wellington, Florida, 33414, United States
Center for Advanced Research & Education

Gainesville, Georgia, 30501, United States
Centro de Investigación Clínica UC-CICUC

Santiago, 8330034, Chile
Charter Research - Lady Lake/The Villages

The Villages, Florida, 32162, United States
Charter Research - Winter Park/Orlando

Orlando, Florida, 32803, United States
Conquest Research, LLC

Winter Park, Florida, 32789, United States
Federation of National Public Service Personnel Mutual Aid Associations Tachikawa Hospital

Tokyo, 190-8531, Japan
Fundación ACE

Barcelona, 08028, Spain
Heidelberg Repatriation Hospital

Heidelberg West, Victoria, 3081, Australia
Hospital Clinic i Provincial

Barcelona, 08036, Spain
Hospital Clinico Univ de Chile

Santiago, 8380456, Chile
Hospital General De Catalunya

Sant Cugat del Vallès, Barcelona, 8195, Spain
Hospital Universitario 12 de Octubre

Madrid, 28041, Spain
Hospital Universitario Dr. Peset

Valencia, 46017, Spain
Hospital Universitario la Fe

Valencia, 46026, Spain
Inha University Hospital

Incheon, 22332, South Korea
JEM Research LLC

Atlantis, Florida, 33462, United States
K2 Medical Research - The Villages

Lady Lake, Florida, 32159, United States
K2 Medical Research, LLC

Maitland, Florida, 32751, United States
K2 Medical Research-Winter Garden

Clermont, Florida, 34711, United States
Keio University Hospital

Tokyo, 160-8582, Japan
Kerwin Research Center, LLC

Dallas, Texas, 75231, United States
Koseikai Takeda Hospital

Kyoto, 600-8558, Japan
NZOZ WCA

Wroc?aw, 53-659, Poland
National Hospital Organization Utano National Hospital

Kyoto, 616-8255, Japan
Optimus U Corp

Miami, Florida, 33135, United States
Osrodek Badan Klinicznych Euromedis

Szczecin, 70-111, Poland
Policlínica Guipuzcoa

Donostia / San Sebastian, Guipuzcoa, 20014, Spain
Quest Research Institute

Farmington Hills, Michigan, 48334, United States
Richmond Clinical Trials

Richmond, British Columbia, V6V 2L1, Canada
Samsung Medical Center

Seoul, 06351, South Korea
Summit Research Network Inc.

Portland, Oregon, 97210, United States
Tokyo Metropolitan Geriatric Hospital

Tokyo, 173-0015, Japan
Toronto Memory Program

Toronto, Ontario, M3B 2S7, Canada
UCL Institute of Neurology

London, WC1N 3BG, United Kingdom
Yokohama City Minato Red Cross Hospital

Kanagawa, 231-8682, Japan

Conditions

Explore the condition pages connected to this study.

ALZHEIMERS DISEASE ALZHEIMERS DISEASE