Custom RNA vaccine shows promise in fighting tough breast cancer

NCT ID NCT02316457

First seen Mar 21, 2026 · Last updated May 16, 2026 · Updated 10 times

Summary

This early-stage study tested a personalized RNA vaccine designed to train the immune system to attack triple negative breast cancer cells. 42 patients received custom-made vaccines based on their tumor's unique genetic makeup. The main goal was to check safety and see if the vaccine could trigger an immune response against the cancer.

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Contacts and locations

Locations

  • Dr. Horst Schmidt-Kliniken Wiesbaden

    Wiesbaden, 65199, Germany

  • Johannes Gutenberg University

    Mainz, RLP, 55131, Germany

  • National Center for Tumor Diseases (NCT)

    Heidelberg, 69120, Germany

  • Uppsala University Hospital

    Uppsala, 75185, Sweden

Conditions

Explore the condition pages connected to this study.