New mpox vaccine shows early promise in safety trial

NCT ID NCT05988203

Summary

This early-stage study tested a new RNA-based vaccine designed to protect against mpox (monkeypox). Researchers enrolled 96 healthy adults, including some who had received a smallpox vaccine decades ago and some who had not. The main goal was to check the vaccine's safety and see if it triggered a protective immune response in participants.

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Contacts and locations

Locations

  • Addenbrooke's Hospital - Cambridge University Hospitals NHS Foundation Trust

    Cambridge, CB2 0QQ, United Kingdom

  • Alliance for Multispecialty Research, LLC

    Kansas City, Missouri, 64114, United States

  • Alliance for Multispecialty Research, LLC

    Knoxville, Tennessee, 37909, United States

  • California Research Foundation

    San Diego, California, 92123, United States

  • Guy's and St Thomas' NHS Foundation Trust of St Thomas' Hospital

    London, SE1 7EH, United Kingdom

  • Medicine Evaluation Unit Ltd, The Langley Building, Wythenshawe Hospital

    Manchester, M239QZ, United Kingdom

  • Royal Surrey County Hospital Foundation Trust, NIHR Royal Surrey Clinical Research Facility

    Guildford, GU2 7XP, United Kingdom

  • University Hospital Southampton

    Southampton, SO16 6YD, United Kingdom

  • University of Washington Virology Research Clinic

    Seattle, Washington, 98104, United States

Conditions

Explore the condition pages connected to this study.