Could a daily pill replace frequent blood tests for heart valve patients?

NCT ID NCT07456085

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares rivaroxaban, a newer blood thinner that doesn't need regular lab monitoring, to the standard drug warfarin in 60 adults with mechanical heart valves. The goal is to see if rivaroxaban can safely prevent blood clots and bleeding complications. Participants will take rivaroxaban once or twice daily along with aspirin, and be followed for one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Rivaroxaban
What this could lead to
If successful, this could offer a simpler, more accessible blood-thinning option for people with mechanical heart valves, reducing the need for frequent lab tests.
What could go wrong
This is a small, early-phase study with only 60 participants, so results may not apply to everyone. Rivaroxaban may not prevent blood clots as well as warfarin in this setting, and bleeding risks remain.

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Conditions

The condition(s) this trial relates to.

heart valve disorder Hemorrhage Thromboembolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Rawalpindi Institute of Cardiology

    Rawalpindi, Punjab Province, 46000, Pakistan

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