New hope for PMR patients: drug may cut steroid dependence
NCT ID NCT05533164
First seen Feb 04, 2026 · Last updated May 15, 2026 · Updated 19 times
Summary
This study tests whether rituximab, a drug that targets certain immune cells, can help people with polymyalgia rheumatica (PMR) stop or reduce their steroid medication. PMR causes pain and stiffness, and long-term steroid use has serious side effects. The trial includes 174 adults with PMR who are unable to lower their steroid dose below 5 mg per day. Researchers will compare how many people achieve steroid-free remission at 52 weeks with rituximab versus placebo.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Sint Maartensklineik
Ubbergen, Gelderland, 6574 NA, Netherlands
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