New hope for chronic hives sufferers: daily pill shows promise in clinical trial

NCT ID NCT07219615

Recruiting now Symptom relief Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Oct 31, 2025 · Last updated May 07, 2026 · Updated 26 times

Summary

This study tests a daily oral medication called ritlecitinib for adults with chronic spontaneous urticaria (CSU) — a condition causing itchy hives and deep skin swelling without a clear trigger. About 200 participants who haven't found relief from antihistamines will be randomly assigned to receive 50 mg, 100 mg, or a placebo for 12 weeks, followed by an extension period. The goal is to see if ritlecitinib safely reduces hive activity and itch severity.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

ALERGO-MED OŚRODEK BADAŃ KLINICZNYCH Sp. z o.o.
NOT_YET_RECRUITING

Tarnów, 33-100, Poland
Acuro Research, Inc.
NOT_YET_RECRUITING

Little Rock, Arkansas, 72205, United States
Allergy Centre Research
RECRUITING

Mississauga, Ontario, L4W 5G6, Canada
Allergy Research Canada Inc.
RECRUITING

Niagara Falls, Ontario, L2H 1H5, Canada
Allergy, Asthma, & Clinical Research Center
RECRUITING

Oklahoma City, Oklahoma, 73120, United States
Antelope Valley Clinical Trials
RECRUITING

Lancaster, California, 93534, United States
Asan Medical Center
RECRUITING

Seoul, Seoul-teukbyeolsi [seoul], 05505, South Korea
Asthma and Allergy Associates, PC
NOT_YET_RECRUITING

Colorado Springs, Colorado, 80907, United States
Asthma and Allergy Center of Chicago
RECRUITING

River Forest, Illinois, 60305, United States
Beijing Friendship Hospital Affiliate of Capital University
NOT_YET_RECRUITING

Beijing, Beijing Municipality, 100050, China
CaRe Clinic
RECRUITING

Red Deer, Alberta, T4P 1K4, Canada
Centre de Recherche Saint-Louis inc.
RECRUITING

Québec, G1W 4R4, Canada
Chang Gung Medical Foundation-Linkou Branch
NOT_YET_RECRUITING

Taoyuan, 333, Taiwan
Charite Universitätsmedizin Berlin Campus Benjamin Franklin
RECRUITING

Berlin, 12203, Germany
Chesapeake Clinical Research
RECRUITING

White Marsh, Maryland, 21162, United States
China Medical University Hospital
RECRUITING

Taichung, 40447, Taiwan
Chung-Ang University Hospital
RECRUITING

Seoul, Seoul-teukbyeolsi [seoul], 06973, South Korea
Clínica Gaias - Santiago
NOT_YET_RECRUITING

Santiago de Compostela, A Coruña [LA Coruña], 15702, Spain
Complete Dermatology
RECRUITING

Sugar Land, Texas, 77479, United States
DAR Clinical Research
NOT_YET_RECRUITING

Ottawa, Ontario, K1V 1C1, Canada
Dar Clinical Research
RECRUITING

Ottawa, Ontario, K2T 0N7, Canada
Dermatology and Ophthalmology Kume Clinic
NOT_YET_RECRUITING

Sakai, Osaka, 593-8324, Japan
Diagnostic Consultative Center 1 - Pernik
NOT_YET_RECRUITING

Pernik, 2300, Bulgaria
ETG Warszawa
NOT_YET_RECRUITING

Warsaw, Masovian Voivodeship, 02-677, Poland
Hattori Dermatology Clinic
NOT_YET_RECRUITING

Takasaki, Gunma, 370-0071, Japan
Hautarztpraxis Dres. Leitz & Kollegen
NOT_YET_RECRUITING

Stuttgart, Baden-Wurttemberg, 70178, Germany
Helios Universitätsklinikum Wuppertal
NOT_YET_RECRUITING

Wuppertal, 42283, Germany
Huashan Hospital, Fudan University
RECRUITING

Shanghai, Shanghai Municipality, 200040, China
Kern Research. Inc.
RECRUITING

Bakersfield, California, 93301, United States
Klinika Osipowicz & Turkowski Sp. z o.o.
NOT_YET_RECRUITING

Warsaw, 00-716, Poland
Korea University Ansan Hospital
RECRUITING

Ansan-si, Kyǒnggi-do, 15355, South Korea
Laser Rejuvenation Clinics Edmonton D.T. Inc
RECRUITING

Edmonton, Alberta, T5J 3S9, Canada
M2M Med Badania Sp. z o.o.
RECRUITING

Chorzów, 41-500, Poland
Medical Center Hera EOOD
RECRUITING

Sofia, 1510, Bulgaria
Medical Center Pulmovision
NOT_YET_RECRUITING

Sofia, 1756, Bulgaria
National Taiwan University Hospital
NOT_YET_RECRUITING

Taipei, 100225, Taiwan
Nomura Dermatology Clinic
NOT_YET_RECRUITING

Yokohama, Kanagawa, 221-0825, Japan
Pusan National University Hospital
RECRUITING

Busan, Pusan-kwangyǒkshi, 49241, South Korea
Revival Research Institute, LLC
RECRUITING

Troy, Michigan, 48084, United States
Severance Hospital, Yonsei University Health System
RECRUITING

Seoul, Seoul-teukbyeolsi [seoul], 03722, South Korea
Skin & Beauty Center - Pasadena
RECRUITING

Pasadena, California, 91105, United States
Tachikawa Dermatology Clinic
NOT_YET_RECRUITING

Tachikawa, Tokyo, 190-0023, Japan
Taipei Medical University - Shuang Ho Hospital, Ministry of Health and Welfare
RECRUITING

New Taipei City, 23561 (R.O.C), Taiwan
The First Hospital of Hebei Medical University
RECRUITING

Shijiazhuang, Hebei, 050031, China
The First People's Hospital of Hangzhou
NOT_YET_RECRUITING

Hangzhou, Zhejiang, 310000, China
The Third Affiliated Hospital Of Sun Yat-Sen University
NOT_YET_RECRUITING

Guangzhou, Guangdong, 510630, China
Tianjin Medical University General Hospital
NOT_YET_RECRUITING

Tianjin, Tianjin Municipality, 300052, China
Trialmed CRS - Warszawa
RECRUITING

Warsaw, 02-482, Poland
University of Michigan
NOT_YET_RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Miyazaki Hospital
NOT_YET_RECRUITING

Miyazaki, 889-1692, Japan
Universitätsklinikum Leipzig
RECRUITING

Leipzig, 04103, Germany
Yokohama Queen's Tower C 8F
NOT_YET_RECRUITING

Yokohama, Kanagawa, 220-6208, Japan

Conditions

Explore the condition pages connected to this study.

CHRONIC SPONTANEOUS URTICARIA