Promising cancer combo trial for kids ends early
NCT ID NCT05429502
First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 24 times
Summary
This study tested a new combination of drugs (ribociclib plus topotecan and temozolomide) in children and young adults with relapsed or treatment-resistant neuroblastoma and other solid tumors. The goal was to see if the combination was safe and effective. The trial was terminated early, and only 12 participants were enrolled.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cohen Children's Medical Center of New York
New Hyde Park, New York, 11040, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Novartis Investigative Site
Cologne, 50937, Germany
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Novartis Investigative Site
Milan, MI, 20133, Italy
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Novartis Investigative Site
Sutton, Surrey, SM2 5PT, United Kingdom
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St Jude s Childrens Research Hospital
Memphis, Tennessee, 38105-2794, United States
Conditions
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