New nasal wash could soothe dry nose sufferers
NCT ID NCT07308015
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a special nasal irrigator that uses sodium hyaluronate to treat rhinitis sicca, a condition causing dry nose, thick mucus, and nosebleeds. Researchers will compare it to a standard seawater spray in 200 adults. The goal is to see if the irrigator better relieves symptoms and improves nasal health.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2025
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Symptoms: Dry nose sensation, little and thick nasal discharge, nosebleeds, itchy nasal cavity, and dryness in the nasopharynx. Physical signs: Nasal endoscopy often reveals dry and congested nasal mucosa, which appears grayish-white or dark red, losing its normal luster. There are often dry, thick secretions, scabs or blood scabs on it. The surface of the nasal mucosa is eroded and ulcers occur. The mucosal lesions are most obvious in the anterior part of the nasal cavity. A diagnosis can be made if one or more of the above symptoms and signs are present. Exclusion Criteria: 1. Those with dry rhinitis and chronic inflammation of the lower respiratory tract. 2. Those confirmed by examination to be caused by certain latent lesions in the mouth, nose, throat, esophagu.s, neck or the whole body 3. Those who have used drugs for treating dry rhinitis or other medications within the past 30 days. 4. Pregnant or lactating women. 5. Those who are allergic to this medicine. 6. Those with severe cardiovascular, liver, kidney and hematopoietic system diseases, etc. 7. Mentally ill patients.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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China-Japan Union Hospital of Jilin University
RECRUITINGChangchun, Jilin, 130000, China