Could better blood matches stop sickle cell patients from making harmful antibodies?

NCT ID NCT04156893

First seen May 01, 2026 · Last updated May 07, 2026 · Updated 1 time

Summary

This study is for people with sickle cell disease who need regular blood transfusions. It tests whether giving blood that closely matches the patient's own blood type (called RH genotype matching) can prevent the body from making antibodies that attack donor blood. About 35 participants will receive these specially matched transfusions to see if it reduces complications and is practical to do on a larger scale.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.