Gene therapy trial offers hope for kids with rare brain disease

NCT ID NCT07236606

First seen Nov 19, 2025 · Last updated May 14, 2026 · Updated 20 times

Summary

This study tests a gene therapy called RGX-121 in children with Hunter syndrome, a rare genetic disorder that affects the brain and body. The therapy delivers a working copy of the missing gene to help improve brain development and reduce harmful substance buildup. The trial is for boys aged 4 months to under 5 years with the severe form of the disease. Researchers are checking if the treatment is safe and effective over several years.

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Contacts and locations

Locations

  • St. Peter's University Hospital

    New Brunswick, New Jersey, 08901, United States

Conditions

Explore the condition pages connected to this study.