Rare nerve disease study could unlock secrets of brain aging
NCT ID NCT07156214
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study is looking at 50 adults with a rare genetic nerve disorder called RFC1-ataxia or CANVAS, which causes problems with balance, coordination, and sensation. Researchers will take blood samples and skin biopsies over 12 months to measure markers of cell stress and damage. The goal is to better understand how the disease progresses and what it might teach us about more common brain diseases like Parkinson's and Alzheimer's.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could identify biological markers that help track disease progression and reveal shared mechanisms with more common neurodegenerative diseases like Parkinson's or Alzheimer's.
- What could go wrong
- This is a small observational study (50 people) with no treatment being tested. It aims to gather knowledge, not to cure or treat the disease. Results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Alma Mater Studiorum University of Bologna
ACTIVE_NOT_RECRUITINGBologna, 40126, Italy
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Department of Neuroscience
RECRUITINGRoma, 00168, Italy