Heat therapy may shrink thyroid lumps without surgery

NCT ID NCT07237373

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether radiofrequency ablation (RFA) can safely reduce symptoms and improve quality of life in adults with benign thyroid nodules. Fifty participants will undergo the procedure and be followed for one year. The goal is to see if this minimally invasive heat treatment can shrink nodules and relieve pressure or appearance issues.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiofrequency ablation (RFA) device

What this could lead to

If it works, this could offer a non-surgical option to shrink thyroid nodules and ease discomfort or cosmetic concerns.

What could go wrong

This is a small, early observational study with only 50 participants. Results may not apply to everyone, and risks like pain, voice changes, or incomplete shrinkage are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

benign thyroid gland neoplasm toxic thyroid adenoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AZ Sint-Jan Brugge

    NOT_YET_RECRUITING

    Bruges, 8000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UZ Gent

    RECRUITING

    Ghent, 9000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UZ Leuven

    NOT_YET_RECRUITING

    Leuven, 3000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact