Heat therapy may shrink thyroid lumps without surgery

NCT ID NCT07237373

Recruiting now Symptom relief Sponsor: University Hospital, Ghent Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether radiofrequency ablation (RFA) can safely reduce symptoms and improve quality of life in adults with benign thyroid nodules. Fifty participants will undergo the procedure and be followed for one year. The goal is to see if this minimally invasive heat treatment can shrink nodules and relieve pressure or appearance issues.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: radiofrequency ablation (RFA) device
What this could lead to: If it works, this could offer a non-surgical option to shrink thyroid nodules and ease discomfort or cosmetic concerns.
What could go wrong: This is a small, early observational study with only 50 participants. Results may not apply to everyone, and risks like pain, voice changes, or incomplete shrinkage are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

benign thyroid gland neoplasm toxic thyroid adenoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BENIGN THYROID NODULE

Contacts and locations

Locations

AZ Sint-Jan Brugge
NOT_YET_RECRUITING

Bruges, 8000, Belgium
UZ Gent
RECRUITING

Ghent, 9000, Belgium
UZ Leuven
NOT_YET_RECRUITING

Leuven, 3000, Belgium

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