New cancer drug's effect on common meds tested in small early trial

NCT ID NCT07372625

First seen Jan 30, 2026 · Last updated Apr 29, 2026 · Updated 13 times

Summary

This early-phase study looks at how a new drug called rezatapopt affects the way the body processes four common medicines (metformin, rosuvastatin, repaglinide, and midazolam) in people with advanced solid tumors that have a specific TP53 Y220C mutation. About 14 participants will take rezatapopt along with these other drugs to measure changes in drug levels and safety. The goal is to understand potential drug interactions, not to treat the cancer directly.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Florida Cancer Specialists

    RECRUITING

    Orlando, Florida, 32827, United States

    Contact Email: •••••@•••••

  • HealthOne Denver

    RECRUITING

    Denver, Colorado, 80237, United States

    Contact Email: •••••@•••••

  • NEXT Oncology

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Email: •••••@•••••

  • SCRI Oncology Partners

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact Email: •••••@•••••

  • SCRI at Mary Crowley

    RECRUITING

    Dallas, Texas, 75230, United States

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.