New drug trial aims to shield vulnerable transplant patients from deadly fungal infections

NCT ID NCT04368559

Summary

This study is testing if a new intravenous drug called Rezafungin works as well as or better than the current standard medications to prevent dangerous fungal infections. It involves 602 adults who are receiving a donor bone marrow transplant for conditions like leukemia. The main goal is to see if patients taking Rezafungin can stay free of fungal infections and survive just as well as those on standard care.

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Contacts and locations

Locations

  • AZ Sint-Jan

    Bruges, West Vlaanderen, 8000, Belgium

  • Addenbrookes Hospital

    Cambridge, cb2 0QQ, United Kingdom

  • Agostino Gemelli University Policlinic

    Rome, 00168, Italy

  • Augusta University Medical Center

    Augusta, Georgia, 30912, United States

  • Fred Hutchinson Cancer Center

    Seattle, Washington, 98108, United States

  • Grenoble Alpes University Hospital Center

    Grenoble, 38043, France

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Hamilton Health Sciences' Juravinski Hospital

    Hamilton, L8V1C3, Canada

  • Henri Mondor Hospital

    Créteil, 94000, France

  • Hospital Clinic of Barcelona

    Barcelona, 08036, Spain

  • Hospital Saint Antoine Ap-Hp

    Paris, 75012, France

  • Humanitas Cancer Center

    Rozzano, 20089, Italy

  • IEO Istituto Europeo di Oncologia

    Milan, 20141, Italy

  • Jean Minjoz Hospital

    Besançon, 25030, France

  • Johannes Gutenberg University Medical Center

    Mainz, 55131, Germany

  • John Hopkins

    Baltimore, Maryland, 21218, United States

  • Kings College Hospital NHS Foundation Trust

    London, SE5 9RS, United Kingdom

  • La Fe University and Polytechnic Hospital

    Valencia, 46026, Spain

  • Lyon-Sud Hospital Center

    Pierre-Bénite, 69495, France

  • Mary Hitchcock Memorial Hospital Dartmouth-Hitchcock

    Lebanon, New Hampshire, 03756, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • McGill University Health Center

    Montreal, H4A3J1, Canada

  • Puerta de Hierro Majadahonda University Hospital

    Majadahonda, 28220, Spain

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • San Martino Polyclinic Hospital

    Genova, 16132, Italy

  • St. George's University Hospitals NHS Foundation Trust

    London, SW17 0QT, United Kingdom

  • Stanford University School of Medicine

    Stanford, California, 94304, United States

  • Stony Brook University Hospital

    Stony Brook, New York, 11794, United States

  • The Royal Marsden Nhs Foundation Trust

    London, SW3 6JJ, United Kingdom

  • The University of Oklahoma College of Medicine

    Oklahoma City, Oklahoma, 73104, United States

  • UCLA Center for Health Sciences

    Los Angeles, California, 90095, United States

  • University Hospital Carl Gustav Carus Dresden

    Dresden, 01307, Germany

  • University Hospital Marques de Valdecilla

    Santander, 39008, Spain

  • University Hospital Münster

    Münster, 48149, Germany

  • University Hospital Ramon y Cajal

    Madrid, 28034, Spain

  • University Hospital Vall d'Hebron

    Barcelona, 08035, Spain

  • University Hospital Wurzburg UKW

    Würzburg, 97080, Germany

  • University Hospital of Bordeaux

    Pessac, 33604, France

  • University Hospital of Cologne

    Cologne, 50937, Germany

  • University Hospital of Limoges

    Limoges, 87042, France

  • University Hospital of Nantes

    Nantes, 44093, France

  • University Hospital of Salamanca

    Salamanca, 37007, Spain

  • University Hospital of Valencia

    Valencia, 46010, Spain

  • University Hospital of Wales

    Cardiff, CF144XW, United Kingdom

  • University Hospitals Geneva

    Geneva, 1211, Switzerland

  • University Hospitals Leuven, Campus Gasthuisberg - UZ Leuven

    Leuven, 3000, Belgium

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of Maryland Medical Center

    Baltimore, Maryland, 21201, United States

  • University of Minnesota Physicians

    Minneapolis, Minnesota, 55455, United States

  • University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 15213, United States

  • VCU Medical Center Main Hospital

    Richmond, Virginia, 23219, United States

Conditions

Explore the condition pages connected to this study.