New hope for rare lung infection: weekly drug shows promise in early trial

NCT ID NCT06794554

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called rezafungin for people with a long-term lung infection caused by a fungus (chronic pulmonary aspergillosis) who have few other treatment choices. About 60 adults will receive the drug once a week for 6 months. Researchers will check if the treatment improves symptoms and lung scans, and monitor for side effects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Asklepios Lungenfachklinik Gauting

    Gauting, Germany

  • Brussels University Hospital

    Brussels, Belgium

  • CHU Amiens Picardie

    Amiens, France

  • CHU Arnaud de Villeneuve

    Montpellier, France

  • CHU Bordeaux

    Pessac, France

  • CHU UCL Namur

    Yvoir, Belgium

  • Chonnam National University Hospital

    Gwangju, South Korea

  • Evangelische Lungenklinik Berlin

    Berlin, Germany

  • Hospital La Fe

    Valencia, Spain

  • Hospital Sant Joan de Deu de Martorell

    Martorell, Spain

  • Hospital Universitari de Bellvitge

    Barcelona, Spain

  • Hospital de la Santa Creu i Sant Pau

    Barcelona, Spain

  • Humanitas Research Hospital

    Rozzano, Italy

  • INMI Lazzaro Spallanzaniconsu

    Roma, Italy

  • Imperial College Hospital

    London, United Kingdom

  • Institut Coeur Poumon CHU

    Lille, France

  • Kepler University Hospital

    Linz, Austria

  • Leeds Teaching Hospital

    Leeds, United Kingdom

  • Manchester University Hospital

    Manchester, United Kingdom

  • Országos Korányi Pulmonológiai Intézet

    Budapest, Hungary

  • Radboud Universitair Medisch Centrum Stichting

    Nijmegen, Netherlands

  • Ramón y Cajal Hospital

    Madrid, Spain

  • Royal Brompton Hospital, Guy's and St. Thomas' Hospital

    London, United Kingdom

  • Royal Papworth Hospital

    Cambridge, United Kingdom

  • Seoul National University Bundang Hospital

    Seoul, South Korea

  • Seoul National University Hospital

    Seoul, South Korea

  • Severance Hospital, Yonsei University Health System

    Seoul, South Korea

  • UZ Gent

    Ghent, Belgium

  • University College London (UCL) Hospitals

    London, United Kingdom

  • University Hospital Leuven

    Leuven, Belgium

  • University Hospitals of Derby and Burton

    Derby, United Kingdom

  • University of Cologne

    Cologne, Germany

  • University of Dundee

    Dundee, United Kingdom

  • University of Genova, San Martino Hospital

    Genova, Italy

  • University of Pisa

    Pisa, Italy

  • Vall d'Hebron Barcelona Hospital Campus

    Barcelona, Spain

  • Western General Hospital

    Edinburgh, United Kingdom

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