New pill aims to shrink liver tumors in patients with advanced disease
NCT ID NCT05440708
First seen Nov 01, 2025 · Last updated May 02, 2026 · Updated 21 times
Summary
This study tests an experimental pill called TTI-101 in people with advanced liver cancer that cannot be removed by surgery. Some participants receive TTI-101 alone, while others get it combined with standard immunotherapy drugs. The main goals are to check safety and see if the drug helps shrink tumors. About 193 adults are being recruited.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Barbara Ann Karmanos Cancer Institute
RECRUITINGDetroit, Michigan, 48201, United States
Contact Phone: •••-•••-••••
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Cleveland Clinic Lerner College of Medicine
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-••••
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DHR Health Institute for Research and Development
RECRUITINGMcAllen, Texas, 78504, United States
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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Froedtert and Medical College of Wisconsin
COMPLETEDMilwaukee, Wisconsin, 53226, United States
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Georgetown Lombardi Comprehensive Cancer Center
COMPLETEDWashington D.C., District of Columbia, 20007, United States
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Harold C. Simmons Comprehensive Cancer Center
RECRUITINGDallas, Texas, 75390, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Memorial Sloan Kettering Cancer Center - New York
RECRUITINGNew York, New York, 10065, United States
Contact
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Norris Comprehensive Cancer Center
RECRUITINGLos Angeles, California, 90033, United States
Contact Email: •••••@•••••
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Summit Cancer Centers - North Spokane
RECRUITINGSpokane, Washington, 99208, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Kirklin Clinic of University of Alabama Birmingham Hospital
RECRUITINGBirmingham, Alabama, 35233, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Sidney Kimmel Comprehensive Cancer Center
RECRUITINGBaltimore, Maryland, 21231, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California Irvine Medical Center
RECRUITINGOrange, California, 92868, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California San Diego
COMPLETEDLa Jolla, California, 92093, United States
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University of Colorado Hospital - Anschutz Medical Campus
RECRUITINGAurora, Colorado, 80045, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Michigan Rogel Cancer Center
RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Oklahoma Health Sciences Center
RECRUITINGOklahoma City, Oklahoma, 73104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Texas Health Science Center - San Antonio
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Texas MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030-4000, United States
Contact Email: •••••@•••••
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Virginia Mason Medical Center
RECRUITINGSeattle, Washington, 98101, United States
Contact Phone: •••-•••-••••
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Washington University in St. Louis
RECRUITINGSt Louis, Missouri, 63129, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.