New drug combo aims to shrink stomach cancer before surgery

NCT ID NCT07493382

First seen Mar 26, 2026 · Last updated May 01, 2026 · Updated 5 times

Summary

This study tests whether adding Retlirafusp alfa to standard chemotherapy before and after surgery can improve outcomes for people with gastroesophageal junction cancer. About 30 adults with HER2-negative, CPS>5 tumors will receive 3 cycles of the drug combo, then surgery, then possibly more Retlirafusp alfa alone. The main goal is to see how many patients have no cancer left after treatment.

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