New immunotherapy combo made available for patients with advanced anal cancer

NCT ID NCT06910137

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This program provides retifanlimab, an immunotherapy drug, together with standard chemotherapy (carboplatin and paclitaxel) to adults with advanced squamous cell carcinoma of the anal canal who cannot join other clinical trials. The goal is to offer a potential treatment option when no others are available. Participants must be in reasonably good health and have no other suitable therapies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

retifanlimab (a type of immunotherapy) combined with carboplatin and paclitaxel (chemotherapy)

What this could lead to

If this works, it could offer a treatment option for people with advanced anal cancer who have run out of standard choices.

What could go wrong

This is an early access program, not a formal trial, so effectiveness and safety are still being studied. It may not work for everyone and can cause side effects like immune reactions or chemotherapy toxicity.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anal canal squamous cell carcinoma anus neoplasm squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••