Filler gel shows promise for sunken temples

NCT ID NCT05691972

First seen May 24, 2026 · Last updated Jun 19, 2026 · Updated 4 times

Summary

This study tested Restylane Contour, a hyaluronic acid gel, for treating temple hollowing in 225 adults. Participants received either the gel or no treatment. Results showed that most treated patients had at least a one-grade improvement on a temple volume scale. The gel is already used for other facial areas, and this trial supports its use for temples.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Galderma Research Site

    Phoenix, Arizona, 85054, United States

  • Galderma Research Site

    Encino, California, 91436, United States

  • Galderma Research Site

    Los Angeles, California, 90069, United States

  • Galderma Research Site

    Redondo Beach, California, 90277, United States

  • Galderma Research Site

    Solana Beach, California, 92075, United States

  • Galderma Research Site

    Vista, California, 92083, United States

  • Galderma Research Site

    Washington D.C., District of Columbia, 20037, United States

  • Galderma Research Site

    Adventura, Florida, 33180, United States

  • Galderma Research Site

    Boynton Beach, Florida, 33437, United States

  • Galderma Research Site

    Coral Gables, Florida, 33146, United States

  • Galderma Research Site

    New Orleans, Louisiana, 70115, United States

  • Galderma Research Site

    New York, New York, 10021, United States

  • Galderma Research Site

    Chapel Hill, North Carolina, 27517, United States

  • Galderma Research Site

    Wilmington, North Carolina, 28405, United States

  • Galderma Research Site

    Nashville, Tennessee, 37203, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Restylane Contour (hyaluronic acid gel with lidocaine)

What this could lead to

If successful, this could provide a safe, effective option for improving temple hollowing, enhancing facial appearance.

What could go wrong

This is a cosmetic treatment, not a cure. Results may vary, and risks include allergic reactions or bruising. The study is completed but not a breakthrough.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.