Which dental restoration lasts longest after root canal?
NCT ID NCT07778563
First seen Aug 21, 2026 · Last updated Aug 21, 2026
Summary
This study tests different methods for restoring molars that have had root canal treatment. It compares zirconia and glass-ceramic onlays cemented with two types of resin cement, plus direct composite fillings made with an injection moulding technique. Thirty patients with two treated molars will receive different restorations to see which approach performs best over three years, looking at durability, complications, cost, and patient satisfaction.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Dental restorative procedures: zirconia and glass-ceramic onlays cemented with different resin cements, and direct composite restorations using injection moulding.
- What this could lead to
- If successful, this could identify the most durable and cost-effective way to restore root canal-treated molars, improving long-term dental outcomes and patient satisfaction.
- What could go wrong
- The trial is small (30 patients) and early, so results may not apply broadly. Restorations can fail due to fractures, cement failure, or complications, and long-term outcomes are uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2031
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Have two endodontically treated molars suitable for restoration, allowing a split-mouth design for the indirect restorations (zirconia and glass-ceramic onlays). Have sufficient tooth structure circumferentially above the gingival margin to allow adequate isolation during restoration cementation. Have controlled periodontal disease and adequate periodontal health for participation. Have maxillary or mandibular molars that are in functional occlusion. Both smokers and non-smokers are eligible to participate. For the direct composite injection moulding group, one suitable endodontically treated molar per participant will be restored. Exclusion Criteria: \-
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.