Brain scans reveal why some people are more susceptible to placebos

NCT ID NCT07479966

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Stefanie Brassen Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether differences in brain connectivity can predict how strongly people respond to placebos. About 50 healthy adults will undergo brain scans and participate in placebo experiments where they receive a nasal spray labeled as oxytocin (but actually just saline). The goal is to understand why some individuals experience stronger placebo effects, which could inform future treatments for mood disorders.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help explain why some people respond to placebos more than others, potentially improving future treatment designs for mood disorders.

What could go wrong

This is a small, early-stage observational study in healthy volunteers, not a treatment trial. Results may not apply to patients with mood disorders or lead to direct clinical benefits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CONDITION: HEALTHY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf

    Hamburg, Free and Hanseatic City of Hamburg, 20246, Germany