Heart valve failure: which fix lasts longer?

NCT ID NCT07462624

Recruiting now Disease control Sponsor: Heart Center Leipzig - University Hospital Source: ClinicalTrials.gov ↗

First seen Mar 12, 2026 · Last updated May 13, 2026 · Updated 6 times

Summary

This study compares two procedures for people whose surgically placed heart valve (bioprosthetic aortic valve) has stopped working properly. One option is repeat open-heart surgery to replace the valve again. The other is a less invasive procedure called valve-in-valve, where a new valve is placed inside the old one using a catheter. The study will follow 890 participants for 5 years to see which approach better prevents death, stroke, heart attack, or the need for another procedure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Herzzentrum Leipzig GmbH
RECRUITING

Leipzig, Saxony, 04289, Germany

Contact Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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DEGENERATIVE AORTIC VALVE DISEASE