New shot could slow blindness in millions

NCT ID NCT06373731

First seen Nov 01, 2025 · Last updated May 04, 2026 · Updated 28 times

Summary

This study tests a daily shot called elamipretide to see if it can slow the loss of light-sensing cells in the eyes of people with dry age-related macular degeneration (AMD). About 313 adults aged 55 and older with early vision damage will receive either the drug or a placebo for up to 96 weeks. The goal is to measure changes in the retina and check for side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Associated Retina Consultants

    Phoenix, Arizona, 85020, United States

  • Associated Vitreoretinal and Uveitis Consultants

    Carmel, Indiana, 46290, United States

  • Augenzentrum am St. Franziskus-Hospital

    Münster, Germany

  • Austin Clinical Research, LLC

    Austin, Texas, 78750, United States

  • Axon Clinical, s.r.o.

    Prague, Czechia

  • Barnet Dulaney Perkins Eye Center

    Sun City, Arizona, 85351, United States

  • Bay Area Retina Associates

    Walnut Creek, California, 94598, United States

  • Capital Eye Specialists

    Wellington, 6011, New Zealand

  • Centro de Oftalmologia Barraquer

    Barcelona, Spain

  • Connecticut Eye Consultants, P.C.

    Danbury, Connecticut, 06810, United States

  • Department für Augenheilkunde

    Tübingen, Germany

  • Department of Ophthalmology, Azienda SanitariaUniversitaria Friuli Centrale

    Udine, Italy

  • Emerson Clinical Research Institute

    Falls Church, Virginia, 22042, United States

  • Florida Retina Institute

    Orlando, Florida, 32806, United States

  • Fondazione Policlinico Gemelli

    Roma, Italy

  • Fundacion Aiken de la Comunitat Valenciana

    Valencia, Spain

  • Ganglion Medical Center

    Pécs, Hungary

  • Hospital Luigi Sacco Ophthalmology Dept

    Milan, Italy

  • IRRCS Ospendale San Raffaele

    Milan, Italy

  • Kellogg Eye Center

    Ann Arbor, Michigan, 48105, United States

  • Klinik und Poliklinik für Augenheilkunde- Universitätsklinik Regensburg

    Regensburg, Germany

  • Macular Services, Central Middlesex Hospital, NHS Foundation Trust

    London, United Kingdom

  • Medical Center Ophthalmology Associates

    San Antonio, Texas, 78240, United States

  • Mid Atlantic Retina

    Cherry Hill, New Jersey, 08034, United States

  • Mid Atlantic Retina Specialist

    Hagerstown, Maryland, 21740, United States

  • NJ Retina

    Teaneck, New Jersey, 07666, United States

  • OMIQ Research

    Barcelona, Spain

  • Oftalvist

    Valencia, Spain

  • Ophthalmic Consultants of Boston

    Boston, Massachusetts, 02114, United States

  • Orange County Retinal Medical Group

    Santa Ana, California, 92705, United States

  • Pacific Northwest Retina, PLLC

    Silverdale, Washington, 98383, United States

  • Policlinico Milano

    Milan, Italy

  • Retina Associates of Southern California

    Huntington Beach, California, 92607, United States

  • Retina Consultants of Minnesota

    Minneapolis, Minnesota, 55435, United States

  • Retina Consultants of San Diego

    Poway, California, 92064, United States

  • Retina Consultants of Southern Colorado

    Colorado Springs, Colorado, 80909, United States

  • Retina Consultants of Texas

    Bellaire, Texas, 77401, United States

  • Retina Consultants of Texas

    The Woodlands, Texas, 77384, United States

  • Retina Northwest, PC

    Portland, Oregon, 97221, United States

  • Retina Research Institute of Texas

    Abilene, Texas, 79606, United States

  • Retina Vitreous Associates of Florida

    St. Petersburg, Florida, 33711, United States

  • Retina Vitreous Center

    Edmond, Oklahoma, 73013, United States

  • Retinal Consultants Medical Group

    Sacramento, California, 95825, United States

  • South Tyneside and Sunderland NHS Foundation Trust - Sunderland Eye Infirmary

    Sunderland, United Kingdom

  • Southern Eye Specialists

    Christchurch, 8013, New Zealand

  • Texas Retina Associates of Plano

    Plano, Texas, 75075, United States

  • University Hospitals Bristol NHS Foundation Trust - Bristol Eye Hospital

    Bristol, United Kingdom

  • University Hospitals of Leicester, Leicester Royal Infirmary

    Leicester, United Kingdom

  • University Of Debrecen Eye Center

    Debrecen, Hungary

  • University Retina and Macula Associates

    Oak Forest, Illinois, 60452, United States

  • University of Szeged, Department of Ophthalmology

    Szeged, Hungary

  • Valley Retina Institute

    McAllen, Texas, 78503, United States

  • Vitreo Retinal Associates

    Gainesville, Florida, 32607, United States

Conditions

Explore the condition pages connected to this study.