New pill targets rosacea inflammation at its source

NCT ID NCT07681271

First seen Jul 02, 2026 · Last updated Aug 13, 2026 · Updated 6 times

Summary

This study tests an oral medication called remibrutinib for adults with moderate-to-severe papulopustular rosacea, a skin condition causing red bumps and pustules on the face. The drug works by blocking a protein involved in inflammation. Researchers will measure whether it reduces the number of facial lesions compared to a placebo, and check for side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
remibrutinib (LOU064)
What this could lead to
If successful, this could offer a new oral treatment option for people with moderate-to-severe papulopustular rosacea, reducing facial bumps and pustules.
What could go wrong
This is an early Phase 2 study with only 80 participants, so results may not confirm effectiveness or safety. The drug may cause side effects or fail to outperform placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Novartis Investigative Site

    RECRUITING

    London, Ontario, N6H 5L5, Canada

  • Novartis Investigative Site

    RECRUITING

    Markham, Ontario, L3P 1X3, Canada

  • Novartis Investigative Site

    RECRUITING

    Dongjak Gu, Seoul, 07061, South Korea

  • Three A Research

    RECRUITING

    El Paso, Texas, 79902, United States

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