Scientists investigate why osimertinib stops working in lung cancer

NCT ID NCT07363252

First seen Jan 23, 2026 · Last updated May 15, 2026 · Updated 13 times

Summary

This study is for people with a specific type of lung cancer (EGFR-mutated NSCLC) whose cancer came back during or after treatment with the drug osimertinib. Researchers will analyze tumor and blood samples to find new genetic changes that may explain why the cancer returned. The goal is to better understand recurrence and guide future treatment options.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

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Locations

  • "OSPEDALE P. PEDERZOLI" Casa di Cura Privata S.p.A.

    ACTIVE_NOT_RECRUITING

    Peschiera del Garda, VR, 37019, Italy

  • A.O.U. "Maggiore della Carita'"- S.C.D.U Oncologia

    NOT_YET_RECRUITING

    Novara, 28100, Italy

    Contact

  • A.S.S.T - Monza Ospedale San Gerardo

    NOT_YET_RECRUITING

    Monza, MB, 20900, Italy

    Contact

  • AOU Integrata di Verona - Ospedale Borgo Trento

    NOT_YET_RECRUITING

    Verona, VR, 37126, Italy

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  • AOU San Luigi Gonzaga - SSD oncologia polmonare

    NOT_YET_RECRUITING

    Orbassano, TO, 10043, Italy

    Contact

  • Asst Papa Giovanni Xxiii Sc Oncologia

    NOT_YET_RECRUITING

    Bergamo, BG, 24127, Italy

    Contact

  • Dip Oncologia-Ematologia - UO Oncologia AOU Policlinico di Modena

    ACTIVE_NOT_RECRUITING

    Modena, Missouri, 41124, Italy

  • European Institute of Oncology IRCCS

    NOT_YET_RECRUITING

    Milan, MI, 20141, Italy

    Contact

  • Fondazione IRCCS Istituto Nazionale dei Tumori di Milano

    NOT_YET_RECRUITING

    Milan, MI, 20113, Italy

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  • Fondazione Policlinico Universitario 'Agostino Gemelli' IRCCS

    NOT_YET_RECRUITING

    Roma, RM, 00168, Italy

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  • Fondazione Policlinico Universitario Campus Bio-Medico

    NOT_YET_RECRUITING

    Roma, RM, 00128, Italy

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  • Grande Ospedale Metropolitano Niguarda Ca' Granda

    ACTIVE_NOT_RECRUITING

    Milan, Michigan, 20162, Italy

  • Humanitas Istituto Clinico Catanese Contrada Cubba

    NOT_YET_RECRUITING

    Misterbianco, CT, 95045, Italy

    Contact

  • IRCCS Oncologico Giovanni Paolo II

    ACTIVE_NOT_RECRUITING

    Bari, BA, 70124, Italy

  • Ifo-Istituto Regina Elena - Oncologia Medica 1

    NOT_YET_RECRUITING

    Roma, RM, 00144, Italy

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  • Irccs Humanitas Research Hospital

    NOT_YET_RECRUITING

    Milan, MI, 20089, Italy

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  • Oncologia Clinica Sperimentale Toraco-Polmonare, IRCCS Pascale di Napoli

    NOT_YET_RECRUITING

    Naples, 80131, Italy

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  • Ospedale San Raffaele Dipartimento di Oncologia Medica

    NOT_YET_RECRUITING

    Milan, MI, 20132, Italy

    Contact

  • S.C. Oncologia Provinciale, Azienda USL-IRCCS di Reggio Emilia

    ACTIVE_NOT_RECRUITING

    Reggio Emilia, RE, 42123, Italy

  • S.O.C. di Oncologia Medica e dei Tumori Immuno-correlati, Centro di Riferimento Oncologico IRCCS

    NOT_YET_RECRUITING

    Aviano, PN, 33081, Italy

    Contact

  • SC Oncologia ASST Sette Laghi "Ospedale di Circolo e Fondazione Macchi "

    NOT_YET_RECRUITING

    Varese, VA, 21100, Italy

    Contact

  • U.O.C. Oncologia Medica Azienda Unità Sanitaria Locale della Romagna

    RECRUITING

    Ravenna, RA, 48100, Italy

    Contact

  • UOC di Oncologia Medica 2 - IOV Istituto Oncologico Veneto

    NOT_YET_RECRUITING

    Padova, PD, 35128, Italy

    Contact

  • UOC di Oncologia Medica Azienda Ospedaliero-Universitaria di Parma

    NOT_YET_RECRUITING

    Parma, PR, 43126, Italy

    Contact

  • UOC di Oncologia Medica IRCCS - Policlinico S. Orsola Malpighi

    NOT_YET_RECRUITING

    Bologna, BO, 40138, Italy

    Contact

Conditions

Explore the condition pages connected to this study.