New combo therapy tested in kids battling tough cancers

NCT ID NCT05255601

Summary

This early-stage study tested a new combination of two immunotherapy drugs (relatlimab and nivolumab) in children and young adults whose Hodgkin or non-Hodgkin lymphoma had come back or did not respond to standard treatments. The main goals were to find a safe dose and see if the treatment showed early signs of helping to control the cancer. Only 5 participants were enrolled to carefully check for side effects and how the drugs behaved in the body.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Assistance Publique-Hopitaux de Paris (AP-HP) - Hopital Armand-Trousseau

    Paris, 75571, France

  • Assistance Publique-Hopitaux de Paris AP-HP - Hopital Universitaire Robert-Debre

    Paris, 75935, France

  • Azienda Ospedale Universita Padova

    Padua, 35128, Italy

  • Azienda Ospedaliero Universitaria di Bologna

    Bologna, 40138, Italy

  • CHRU de Strasbourg-Hopital de Hautepierre

    Strasbourg, 67000, France

  • CHU dAngers - Pole Pediatrie

    Angers, Angers Cedex 9, 49933, France

  • Centre Hospitalier Universitaire de Montpellier CHU Montpellier - Hopital Arnaud de Villeneuve

    Montpellier, 34295, France

  • Fondazione IRCCS Istituto Nazionale Dei Tumori

    Milan, Milano, 20133, Italy

  • Fondazione MBBM - Clinica Pediatrica

    Monza, 20900, Italy

  • Groupe Hospitalier Pellegrin - Hopital des enfants

    Bordeaux, 33076, France

  • Institut d Hematologie et d Oncologie Pediatriques

    Lyon, 69373 Cedex 08, France

  • Local Institution - 0002

    Roma, 00165, Italy

  • Local Institution - 0004

    Turin, 10126, Italy

  • Local Institution - 0010

    Aviano, 33081, Italy

  • Local Institution - 0020

    Jackson, Mississippi, 39216, United States

  • Local Institution - 0023

    Seville, 41013, Spain

  • Local Institution - 0024

    Phoenix, Arizona, 85016, United States

  • Local Institution - 0025

    Minneapolis, Minnesota, 55454, United States

  • Local Institution - 0026

    San Antonio, Texas, 78207, United States

  • Local Institution - 0029

    Austin, Texas, 78723, United States

  • Local Institution - 0030

    Madrid, 28009, Spain

  • Local Institution - 0032

    New Haven, Connecticut, 06510, United States

  • Local Institution - 0033

    Caen, 14033, France

  • Local Institution - 0035

    Palo Alto, California, 94304, United States

  • Local Institution - 0037

    Randwick, New South Wales, 2031, Australia

  • Local Institution - 0040

    Florence, 50139, Italy

  • Local Institution - 0041

    Pavia, 27100, Italy

  • Local Institution - 0042

    Nedlands, Western Australia, 6009, Australia

  • Local Institution - 0044

    Madrid, 28040, Spain

  • Local Institution - 0045

    Madrid, 28046, Spain

  • Local Institution - 0046

    Barcelona, 08035, Spain

  • Local Institution - 0049

    Valencia, 46026, Spain

  • Local Institution - 0053

    London, SM2 5PT, United Kingdom

  • Local Institution - 0054

    London, Londonderry, NW1 2PG, United Kingdom

  • Local Institution - 0055

    Madrid, 28041, Spain

  • Local Institution - 0058

    Madrid, 28027, Spain

  • Local Institution - 0059

    Valhalla, New York, 10595, United States

  • Local Institution - 0060

    New York, New York, 10032, United States

  • Local Institution - 0062

    Pamplona, 31008, Spain

  • Local Institution - 0066

    Fort Myers, Florida, 33908, United States

  • Local Institution - 0067

    La Tronche, 38700, France

  • Local Institution - 0068

    Newcastle upon Tyne, Tyne and Wear, NE1 4LP, United Kingdom

  • Local Institution - 0069

    Esplugues de Llobregat, Barcelona, 08950, Spain

  • Local Institution - 0070

    Milan, 20162, Italy

  • Local Institution - 0071

    Hackensack, New Jersey, 07601, United States

  • Local Institution - 0073

    Baltimore, Maryland, 21287, United States

  • Local Institution - 0074

    Liverpool, England, L12 2AP, United Kingdom

  • Local Institution - 0075

    Cambridge, Cambridgeshire, CB2 0QQ, United Kingdom

  • Local Institution - 0077

    Birmingham, Alabama, 35233, United States

  • Princess Maxima Center for pediatric oncology

    Utrecht, 3584 CS, Netherlands

  • Royal Childrens Hospital RCH - Queensland Childrens Hospital

    South Brisbane, Queensland, 4101, Australia

Conditions

Explore the condition pages connected to this study.