New combo therapy tested in kids battling tough cancers
NCT ID NCT05255601
Summary
This early-stage study tested a new combination of two immunotherapy drugs (relatlimab and nivolumab) in children and young adults whose Hodgkin or non-Hodgkin lymphoma had come back or did not respond to standard treatments. The main goals were to find a safe dose and see if the treatment showed early signs of helping to control the cancer. Only 5 participants were enrolled to carefully check for side effects and how the drugs behaved in the body.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Assistance Publique-Hopitaux de Paris (AP-HP) - Hopital Armand-Trousseau
Paris, 75571, France
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Assistance Publique-Hopitaux de Paris AP-HP - Hopital Universitaire Robert-Debre
Paris, 75935, France
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Azienda Ospedale Universita Padova
Padua, 35128, Italy
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Azienda Ospedaliero Universitaria di Bologna
Bologna, 40138, Italy
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CHRU de Strasbourg-Hopital de Hautepierre
Strasbourg, 67000, France
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CHU dAngers - Pole Pediatrie
Angers, Angers Cedex 9, 49933, France
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Centre Hospitalier Universitaire de Montpellier CHU Montpellier - Hopital Arnaud de Villeneuve
Montpellier, 34295, France
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Fondazione IRCCS Istituto Nazionale Dei Tumori
Milan, Milano, 20133, Italy
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Fondazione MBBM - Clinica Pediatrica
Monza, 20900, Italy
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Groupe Hospitalier Pellegrin - Hopital des enfants
Bordeaux, 33076, France
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Institut d Hematologie et d Oncologie Pediatriques
Lyon, 69373 Cedex 08, France
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Local Institution - 0002
Roma, 00165, Italy
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Local Institution - 0004
Turin, 10126, Italy
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Local Institution - 0010
Aviano, 33081, Italy
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Local Institution - 0020
Jackson, Mississippi, 39216, United States
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Local Institution - 0023
Seville, 41013, Spain
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Local Institution - 0024
Phoenix, Arizona, 85016, United States
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Local Institution - 0025
Minneapolis, Minnesota, 55454, United States
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Local Institution - 0026
San Antonio, Texas, 78207, United States
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Local Institution - 0029
Austin, Texas, 78723, United States
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Local Institution - 0030
Madrid, 28009, Spain
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Local Institution - 0032
New Haven, Connecticut, 06510, United States
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Local Institution - 0033
Caen, 14033, France
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Local Institution - 0035
Palo Alto, California, 94304, United States
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Local Institution - 0037
Randwick, New South Wales, 2031, Australia
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Local Institution - 0040
Florence, 50139, Italy
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Local Institution - 0041
Pavia, 27100, Italy
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Local Institution - 0042
Nedlands, Western Australia, 6009, Australia
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Local Institution - 0044
Madrid, 28040, Spain
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Local Institution - 0045
Madrid, 28046, Spain
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Local Institution - 0046
Barcelona, 08035, Spain
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Local Institution - 0049
Valencia, 46026, Spain
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Local Institution - 0053
London, SM2 5PT, United Kingdom
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Local Institution - 0054
London, Londonderry, NW1 2PG, United Kingdom
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Local Institution - 0055
Madrid, 28041, Spain
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Local Institution - 0058
Madrid, 28027, Spain
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Local Institution - 0059
Valhalla, New York, 10595, United States
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Local Institution - 0060
New York, New York, 10032, United States
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Local Institution - 0062
Pamplona, 31008, Spain
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Local Institution - 0066
Fort Myers, Florida, 33908, United States
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Local Institution - 0067
La Tronche, 38700, France
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Local Institution - 0068
Newcastle upon Tyne, Tyne and Wear, NE1 4LP, United Kingdom
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Local Institution - 0069
Esplugues de Llobregat, Barcelona, 08950, Spain
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Local Institution - 0070
Milan, 20162, Italy
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Local Institution - 0071
Hackensack, New Jersey, 07601, United States
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Local Institution - 0073
Baltimore, Maryland, 21287, United States
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Local Institution - 0074
Liverpool, England, L12 2AP, United Kingdom
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Local Institution - 0075
Cambridge, Cambridgeshire, CB2 0QQ, United Kingdom
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Local Institution - 0077
Birmingham, Alabama, 35233, United States
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Princess Maxima Center for pediatric oncology
Utrecht, 3584 CS, Netherlands
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Royal Childrens Hospital RCH - Queensland Childrens Hospital
South Brisbane, Queensland, 4101, Australia
Conditions
Explore the condition pages connected to this study.