New drug cocktail shows promise against tough liver cancer

NCT ID NCT05194293

First seen Oct 31, 2025 · Last updated Apr 28, 2026 · Updated 30 times

Summary

This study tests whether combining regorafenib (a drug that blocks cancer cell growth) with durvalumab (an immunotherapy that helps the immune system attack cancer) can shrink tumors in people with high-risk liver cancer. About 4 adults with advanced liver cancer that hasn't spread widely will receive the treatment before possible surgery. The goal is to see if the combination makes tumors smaller and easier to remove.

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Contacts and locations

Locations

  • Emory University Hospital/Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • University of Alabama at Birmingham Cancer Center

    Birmingham, Alabama, 35233, United States

Conditions

Explore the condition pages connected to this study.