New drug combo offers hope for Tough-to-Treat colon cancer
NCT ID NCT03829462
First seen Nov 21, 2025 · Last updated May 08, 2026 · Updated 18 times
Summary
This study tests whether combining two drugs (regorafenib and irinotecan) works better than regorafenib alone for people with metastatic colorectal cancer who have run out of standard treatment options. About 377 adults with a specific genetic marker (A/A genotype of cyclin D1) will take part. The goal is to see if the combination helps them live longer.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CRLC Val d'Aurelle-Paul Lamarque
Montpellier, 34298, France
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Centre Antoine Lacassagne
Nice, Alpes-Maritimes, 06189, France
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Centre François Baclesse
Caen, Basse-Normandie, 14000, France
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Centre Léon Bérard
Lyon, Rhône, 69008, France
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Hôpital Européen Georges Pompidou
Paris, 75015, France
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Hôpital Pontchaillou
Rennes, Ile Et Vilaine, 35000, France
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Hôpital Robert Debré
Reims, Marne, 51100, France
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Hôpital Saint-Jean
Perpignan, Pyrénées-orientales, 66000, France
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Hôpital privé Jean Mermoz
Lyon, Rhône, 69008, France
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Institut Godinot
Reims, Marne, 51100, France
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Institut Gustave Roussy
Villejuif, Val De Marne, 94800, France
Conditions
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