Next-Generation polio vaccine enters human testing

NCT ID NCT07688369

First seen Jul 07, 2026 · Last updated Jul 10, 2026 · Updated 2 times

Summary

This trial tests a new recombinant polio vaccine (rPV) against the current standard IPOL vaccine in healthy adults aged 18 to 60. The goal is to see if the new vaccine is safe and triggers a strong immune response. It is a small, early-stage study to gather initial data.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Recombinant Poliomyelitis Vaccine (rPV)
What this could lead to
If successful, this could lead to a more modern, potentially easier-to-produce polio vaccine to help maintain global polio immunity.
What could go wrong
This is an early phase 1 trial with only 36 healthy adults, so safety and immune response are still being tested. The vaccine may not work as well as the current one or could have unexpected side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Doherty Clinical Trials Limited

    East Melbourne, Victoria, 3002, Australia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••