Blood filtering may revive bladder cancer treatment

NCT ID NCT07087860

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 22 times

Summary

This study tests whether a procedure called therapeutic plasma exchange (TPE) can make standard cancer drugs work again for people with advanced bladder or urinary tract cancer that has stopped responding to treatment. TPE filters the blood to remove certain components, then returns the cleaned blood to the body. About 70 adults will be randomly assigned to receive TPE plus the drugs enfortumab vedotin and pembrolizumab, or the usual next treatment. The goal is to see if TPE can improve response rates.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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