Drug trial halted for rare brain tumor condition

NCT ID NCT05130866

Summary

This study tested an investigational drug called REC-2282 to see if it could slow or stop the growth of brain tumors (meningiomas) in people with Neurofibromatosis Type 2 (NF2). It involved about 25 participants aged 12 and older with progressive tumors. The trial was designed in two parts: first to find a safe dose, and then to compare the drug's effectiveness against a placebo, but the study was terminated early.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Children's National Hospital

    Washington D.C., District of Columbia, 20010, United States

  • Columbia University

    New York, New York, 10032, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • House Institute

    Los Angeles, California, 90057, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Nicklaus Children's Hospital

    Miami, Florida, 33155, United States

  • Sarah Cannon Cancer Institute - HCA Midwest

    Overland Park, Kansas, 66211, United States

  • UT Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • University of California Los Angeles

    Los Angeles, California, 90095, United States

  • University of Florida

    Gainesville, Florida, 32611, United States

  • University of Minnesota / Masonic Cancer Center

    Minneapolis, Minnesota, 55455, United States

Conditions

Explore the condition pages connected to this study.