Could a breastfeeding drug mend broken hearts after childbirth?

NCT ID NCT05180773

First seen Nov 01, 2025 · Last updated May 05, 2026 · Updated 25 times

Summary

This study tests whether bromocriptine, a drug that stops breastfeeding, can help women with a rare pregnancy-related heart condition called peripartum cardiomyopathy recover heart function. About 250 women will be randomly assigned to receive bromocriptine or a placebo, and their heart strength will be measured at 6 and 12 months. The goal is to see if the drug improves survival and reduces the need for heart transplants or assist devices.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Albert Einstein College of Medicine/ Montefiore Medical Center

    RECRUITING

    The Bronx, New York, 10461, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ascension St. Vincent Heart Center

    RECRUITING

    Indianapolis, Indiana, 46260, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Atrium Health Sanger Heart and Vascular Institute

    RECRUITING

    Charlotte, North Carolina, 28204, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Baylor College of Medicine

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cedars-Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cleveland Clinic

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Columbia University Irving Medical Center

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Emory University

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hartford Hospital

    RECRUITING

    Hartford, Connecticut, 06106, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Henry Ford Health System

    RECRUITING

    Detroit, Michigan, 48202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Indiana University/Indiana University Health

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Inova Healthcare Services

    RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Intermountain Medical Center

    RECRUITING

    Murray, Utah, 84107, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Johns Hopkins University

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Karen L Florio, MD

    RECRUITING

    Columbia, Missouri, 65201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Keck School of Medicine of USC

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Lehigh Valley Health Network

    WITHDRAWN

    Allentown, Pennsylvania, 18105, United States

  • Louisiana State University

    RECRUITING

    Shreveport, Louisiana, 71103, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mayo Clinic, Florida

    RECRUITING

    Jacksonville, Florida, 32216, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic, Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Minneapolis Heart Institute Foundation

    RECRUITING

    Minneapolis, Minnesota, 55407, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mount Sinai Hospital

    RECRUITING

    New York, New York, 10029, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NYU Langone Health

    RECRUITING

    New York, New York, 10022, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Oklahoma university Health Science Center

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Old Dominion University

    RECRUITING

    Norfolk, Virginia, 23507, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Penn State Hershey Medical Center

    RECRUITING

    Hershey, Pennsylvania, 17033, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rhode Island Hospital

    RECRUITING

    Providence, Rhode Island, 02903, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Saint Luke's Hospital of Kansas City

    RECRUITING

    Kansas City, Missouri, 64154, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stanford University

    RECRUITING

    Stanford, California, 94305, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stern Cardiovascular Foundation, Inc

    RECRUITING

    Germantown, Tennessee, 38138, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stony Brook Medicine

    RECRUITING

    Stony Brook, New York, 11794, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Temple Heart and Vascular Institute

    RECRUITING

    Philadelphia, Pennsylvania, 19140, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UT Southern Medical Center

    WITHDRAWN

    Dallas, Texas, 75390-8830, United States

  • University Hospitals, Cleveland Medical Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Alabama Birmingham

    RECRUITING

    Birmingham, Alabama, 35205, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Arizona Sarver Heart Center

    RECRUITING

    Tucson, Arizona, 85724, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California Irvine Health

    RECRUITING

    Orange, California, 92868, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California San Diego

    RECRUITING

    La Jolla, California, 92037-7411, United States

    Contact

    Contact Email: •••••@•••••

  • University of Colorado Anschutz Medical Campus

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Florida

    RECRUITING

    Gainesville, Florida, 32608, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Illinois Health Heart Center

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Iowa Hospitals and Clinic

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Kentucky, Gill Heart & Vascular Institute

    RECRUITING

    Lexington, Kentucky, 40536, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Maryland Medical Center, Baltimore

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • University of Pittsburgh Medical Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15237, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Rochester

    RECRUITING

    Rochester, New York, 14642, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of South Florida

    RECRUITING

    Tampa, Florida, 33606, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Texas Health San Antonio

    WITHDRAWN

    San Antonio, Texas, 78229, United States

  • University of Vermont Medical Center

    RECRUITING

    Burlington, Vermont, 05401, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Virginia

    RECRUITING

    Charlottesville, Virginia, 22908, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • University of Washington Medical Center

    RECRUITING

    Seattle, Washington, 98195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Wisconsin Madison

    RECRUITING

    Madison, Wisconsin, 53792, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vanderbilt

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact

    Contact Email: •••••@•••••

  • Virginia Commonwealth University

    RECRUITING

    Richmond, Virginia, 23298, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yale University

    RECRUITING

    New Haven, Connecticut, 06520, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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