New study to test antifungal drug safety in organ transplant patients

NCT ID NCT07656493

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study will observe 120 solid organ transplant recipients who have invasive fungal infections. Researchers will track how well the drug liposomal amphotericin B works and its side effects, compared to historical patients who received other antifungal treatments. The goal is to gather real-world evidence to guide better dosing and monitoring in this high-risk group.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Liposomal amphotericin B (an antifungal drug)
What this could lead to
If successful, this study could provide real-world data to help doctors better treat fungal infections in transplant patients, potentially improving survival and reducing side effects.
What could go wrong
This is an observational study, not a controlled trial, so results may be influenced by other factors. It is also small (120 participants) and single-center, limiting how widely findings can be applied.

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Conditions

The condition(s) this trial relates to.

Invasive Fungal Infections Opportunistic Infections opportunistic infectious systemic mycosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital

    Chengdu, Sichuan, 610072, China

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