One blood transfusion could prevent ventilator setbacks in ICU

NCT ID NCT07499492

First seen Jun 25, 2026 · Last updated Jul 10, 2026 · Updated 3 times

Summary

This study tests whether giving a single unit of red blood cells to high-risk ICU patients right before removing the breathing tube can prevent the need to put the tube back in or reduce deaths within 7 days. The trial plans to enroll 800 adults who have been on a ventilator for at least 24 hours and are at high risk of complications. Half will get the transfusion plus standard care, and half will get standard care alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Red blood cell transfusion
What this could lead to
If it works, this could provide a simple way to reduce dangerous complications like reintubation in ICU patients being taken off ventilators.
What could go wrong
This trial hasn't started yet, and the benefit of transfusion must be weighed against risks like infection or transfusion reactions. Results may not apply to all ICU patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.