New drug shows promise for rare post-transplant complication in kids
NCT ID NCT04557735
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a drug called ravulizumab in 41 children who developed a serious blood clotting problem (TMA) after a stem cell transplant. The goal was to see if the drug could help control the condition and improve blood counts and kidney function. The treatment lasted 26 weeks, and children were monitored for another 26 weeks after stopping the drug.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Research Site
Tucson, Arizona, 85724, United States
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Aurora, Colorado, 80045, United States
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Atlanta, Georgia, 30322, United States
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Chicago, Illinois, 60611, United States
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Portland, Oregon, 97239, United States
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Dallas, Texas, 75235, United States
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Salt Lake City, Utah, 84108, United States
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Madison, Wisconsin, 53792, United States
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Haifa, 91096, Israel
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Jerusalem, 91120, Israel
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Petah Tikva, 4920235, Israel
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Ramat Gan, 5265601, Israel
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Roma, 00165, Italy
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Fukushima, 960-1295, Japan
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Kobe, 650-0047, Japan
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Nagoya, 466-8560, Japan
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Osaka, 534-0021, Japan
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Seoul, 03080, South Korea
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Seoul, 5505, South Korea
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Barcelona, 08041, Spain
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Esplugues de Llobregat, 8950, Spain
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Madrid, 28046, Spain
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Salamanca, 37007, Spain
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Birmingham, B4 6NH, United Kingdom
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Bristol, BS2 8BJ, United Kingdom
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Research Site
Newcastle upon Tyne, NE1 4LP, United Kingdom