New hope for kids with rare Post-Transplant blood disorder?

NCT ID NCT04557735

First seen Nov 01, 2025 · Last updated May 11, 2026 · Updated 31 times

Summary

This study tested a drug called ravulizumab in 41 children who developed a serious blood clotting problem (thrombotic microangiopathy) after a stem cell transplant. The treatment was given for 26 weeks, and researchers checked if it helped improve blood counts and kidney function. The goal was to see if the drug is safe and effective for this condition.

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Contacts and locations

Locations

  • Research Site

    Tucson, Arizona, 85724, United States

  • Research Site

    Aurora, Colorado, 80045, United States

  • Research Site

    Atlanta, Georgia, 30322, United States

  • Research Site

    Chicago, Illinois, 60611, United States

  • Research Site

    Portland, Oregon, 97239, United States

  • Research Site

    Dallas, Texas, 75235, United States

  • Research Site

    Salt Lake City, Utah, 84108, United States

  • Research Site

    Madison, Wisconsin, 53792, United States

  • Research Site

    Haifa, 91096, Israel

  • Research Site

    Jerusalem, 91120, Israel

  • Research Site

    Petah Tikva, 4920235, Israel

  • Research Site

    Ramat Gan, 5265601, Israel

  • Research Site

    Roma, 00165, Italy

  • Research Site

    Fukushima, 960-1295, Japan

  • Research Site

    Kobe, 650-0047, Japan

  • Research Site

    Nagoya, 466-8560, Japan

  • Research Site

    Osaka, 534-0021, Japan

  • Research Site

    Seoul, 03080, South Korea

  • Research Site

    Seoul, 5505, South Korea

  • Research Site

    Barcelona, 08041, Spain

  • Research Site

    Esplugues de Llobregat, 8950, Spain

  • Research Site

    Madrid, 28046, Spain

  • Research Site

    Salamanca, 37007, Spain

  • Research Site

    Birmingham, B4 6NH, United Kingdom

  • Research Site

    Bristol, BS2 8BJ, United Kingdom

  • Research Site

    Newcastle upon Tyne, NE1 4LP, United Kingdom

Conditions

Explore the condition pages connected to this study.