New hope for kids with dangerous transplant complication

NCT ID NCT04557735

Summary

This study tested a medication called ravulizumab in children who developed a dangerous blood clotting disorder (TMA) after a stem cell transplant. The goal was to see if adding this drug to standard care could help control the disorder by improving blood counts and kidney function. Forty-one children under 18 received the drug through an IV for 26 weeks, followed by 26 weeks of observation.

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Contacts and locations

Locations

  • Research Site

    Tucson, Arizona, 85724, United States

  • Research Site

    Aurora, Colorado, 80045, United States

  • Research Site

    Atlanta, Georgia, 30322, United States

  • Research Site

    Chicago, Illinois, 60611, United States

  • Research Site

    Portland, Oregon, 97239, United States

  • Research Site

    Dallas, Texas, 75235, United States

  • Research Site

    Salt Lake City, Utah, 84108, United States

  • Research Site

    Madison, Wisconsin, 53792, United States

  • Research Site

    Haifa, 91096, Israel

  • Research Site

    Jerusalem, 91120, Israel

  • Research Site

    Petah Tikva, 4920235, Israel

  • Research Site

    Ramat Gan, 5265601, Israel

  • Research Site

    Roma, 00165, Italy

  • Research Site

    Fukushima, 960-1295, Japan

  • Research Site

    Kobe, 650-0047, Japan

  • Research Site

    Nagoya, 466-8560, Japan

  • Research Site

    Osaka, 534-0021, Japan

  • Research Site

    Seoul, 03080, South Korea

  • Research Site

    Seoul, 5505, South Korea

  • Research Site

    Barcelona, 08041, Spain

  • Research Site

    Esplugues de Llobregat, 8950, Spain

  • Research Site

    Madrid, 28046, Spain

  • Research Site

    Salamanca, 37007, Spain

  • Research Site

    Birmingham, B4 6NH, United Kingdom

  • Research Site

    Bristol, BS2 8BJ, United Kingdom

  • Research Site

    Newcastle upon Tyne, NE1 4LP, United Kingdom

Conditions

Explore the condition pages connected to this study.